CRISPR

CRISPR1-cobll1a

ID

ZDB-CRISPR-241217-7

Name

CRISPR1-cobll1a

Previous Names

None

Target

cobll1a (1)

Sequence

5' - ACCAGTTATGGATGTTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hn15	cobll1a
hn16	cobll1a
hn17	cobll1a

Expression

Gene expression in Wild Types + CRISPR1-cobll1a

No data available

Phenotype

Phenotype resulting from CRISPR1-cobll1a

No data available

Phenotype of all Fish created by or utilizing CRISPR1-cobll1a

Phenotype	Fish	Conditions	Figures
notochord cobll1a expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 2 from Zeng et al., 2024
whole organism apoa4b.1 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
intestine fabp2 expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
whole organism fabp2 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
liver fabp10a expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
exocrine pancreas prss1 expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
lipid catabolic process decreased process quality, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism rargb expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism fabp10a expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
retinoic acid metabolic process decreased process quality, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism apoea expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
whole organism rarab expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism prss1 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
lipid metabolic process increased process quality, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
head decreased size, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 2 from Zeng et al., 2024
lipoprotein metabolic process decreased process quality, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
whole organism cobll1a expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 2 from Zeng et al., 2024
whole organism aldh1a2 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
intestine aldh1a2 expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
intestine rdh10b expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
trunk aldh1a2 expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism rarga expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism srebf2 expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism raraa expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism cyp26a1 expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism apoa1a expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
eye decreased size, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 2 from Zeng et al., 2024
whole organism apoa4a expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
whole organism elovl2 expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism ins expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
whole organism lpla expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism srebf1 expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
eye aldh1a2 expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
endocrine pancreas ins expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
whole organism rbp4 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism apoeb expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
liver rbp4 expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism cp expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
whole organism apoba expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
liver cyp26a1 expression increased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism fasn expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism apobb.1 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
coelom increased size, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 2 from Zeng et al., 2024
whole organism apoa1b expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
adipose tissue increased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
adipose tissue fasn expression increased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism dgat1a expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
notochord cobll1a expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 2 from Zeng et al., 2024
whole organism hhex expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 3 from Zeng et al., 2024
whole organism apoa2 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 7 from Zeng et al., 2024
whole organism stra6 expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism lipca expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism rdh10b expression decreased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024
whole organism scd expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
whole organism elovl6 expression increased amount, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 6 from Zeng et al., 2024
liver aldh1a2 expression decreased distribution, abnormal	cobll1a^hn17/hn17 (TU)	standard conditions	FIGURE 5 from Zeng et al., 2024

Citations