CRISPR

CRISPR1-pparg

ID
ZDB-CRISPR-211116-4
Name
CRISPR1-pparg
Previous Names
None
Target
Sequence
5' - GGGCTTCGGCCTGAGCGCTC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 11
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ecn6 pparg
1 - 1 of 1
Expression
Gene expression in Wild Types + CRISPR1-pparg
No data available
Phenotype
Phenotype resulting from CRISPR1-pparg
No data available
Phenotype of all Fish created by or utilizing CRISPR1-pparg
Phenotype Fish Conditions Figures
liver triglyceride decreased amount, exacerbated ppargecn6/ecn6 (AB) chemical treatment by diet: (R)-carnitine Fig. 6 from Wang et al., 2022
liver fatty acid amount, ameliorated ppargecn6/ecn6 (AB) chemical treatment by diet: N-acetyl-L-cysteine Fig. 5 from Wang et al., 2022
liver reactive oxygen species amount, ameliorated ppargecn6/ecn6 (AB) chemical treatment by diet: (R)-carnitine Fig. 6 from Wang et al., 2022
female organism antioxidant activity increased process quality, abnormal ppargecn6/ecn6 (AB) chemical treatment by diet: N-acetyl-L-cysteine Fig. 5 from Wang et al., 2022
female organism ddit3 expression amount, ameliorated ppargecn6/ecn6 (AB) chemical treatment by diet: N-acetyl-L-cysteine Fig. 5 from Wang et al., 2022
1 - 5 of 94 Show all
Citations
TSV
1 - 2 of 2
Show
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.