CRISPR

CRISPR3-hmx2

ID
ZDB-CRISPR-210802-1
Name
CRISPR3-hmx2
Previous Names
None
Target
Sequence
5' - GGTTCCAGGATAATACAGTG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
Df(Chr17:hmx3a,hmx2)su44 hmx2, hmx3a
Df(Chr17:hmx3a,hmx2)su45 hmx2, hmx3a
su38 hmx2
su39 hmx2
Expression
Gene expression in Wild Types + CRISPR3-hmx2
No data available
Phenotype
Phenotype resulting from CRISPR3-hmx2
No data available
Phenotype of all Fish created by or utilizing CRISPR3-hmx2
Phenotype Fish Conditions Figures
neuromast primordium migration disrupted, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 4 with image,  Figure 5 with image from England et al., 2020
otolith fused with otolith, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 4 with image,  Figure 5 with image from England et al., 2020
anterior macula fused with posterior macula, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 5 with image from England et al., 2020
spinal cord GABAergic neuron gad1b expression increased amount, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 6 with image from England et al., 2020
spinal cord inhibitory interneuron increased amount, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 6 with image from England et al., 2020
spinal cord GABAergic neuron increased amount, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 6 with image from England et al., 2020
spinal cord glutamatergic neuron decreased amount, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 5 with image from England et al., 2020
inner ear anterior region pax5 expression decreased amount, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 5 with image from England et al., 2020
spinal cord inhibitory interneuron slc32a1 expression increased amount, abnormal Df(Chr17:hmx3a,hmx2)su44/su44 standard conditions Figure 6 with image from England et al., 2020
neuromast primordium migration disrupted, abnormal Df(Chr17:hmx3a,hmx2)su45/su45 standard conditions Figure 4 with image from England et al., 2020
otolith fused with otolith, abnormal Df(Chr17:hmx3a,hmx2)su45/su45 standard conditions Figure 4 with image from England et al., 2020
Citations
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