ZFIN ID: ZDB-GENE-080506-2
Gene Name: H6 family homeobox 2
Gene Symbol: hmx2    Nomenclature History

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Previous Name: nkx5.2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Involved in inner ear morphogenesis and posterior lateral line development. Predicted to localize to the nucleus. Is expressed in nervous system and otic vesicle. Orthologous to human HMX2 (H6 family homeobox 2).
Genome Resources: Alliance (1),  Gene:555632 (1),  Ensembl(GRCz11):ENSDARG00000070954 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-hmx2 N/A 1
MO2-hmx2 N/A 1
MO3-hmx2 N/A 1
DISEASE ASSOCIATED WITH hmx2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hmx2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process inner ear morphogenesis (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001356 Homeobox domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR020479 Homeobox domain, metazoa
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hmx2-201 (1)    Ensembl 1331
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hmx2 No data available
MARKER RELATIONSHIPS
hmx2 Contained in: [BAC] CH211-208G24
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001115098 (1) 873 bp
Genomic GenBank:AL773596 (1) 206778 bp Blast at MegaBLAST
Polypeptide UniProtKB:F1QTJ6 (1) 269 aa
Sequence Information (all 10)
ORTHOLOGY for hmx2 ( Chr: 17 )
CITATIONS (24)