CRISPR

CRISPR2-mdka

ID

ZDB-CRISPR-200124-20

Name

CRISPR2-mdka

Previous Names

None

Target

mdka (1)

Sequence

5' - TTCCACCCTCCTCGTGGTGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
cn105	mdka

Expression

Gene expression in Wild Types + CRISPR2-mdka

No data available

Phenotype

Phenotype resulting from CRISPR2-mdka

No data available

Phenotype of all Fish created by or utilizing CRISPR2-mdka

Phenotype	Fish	Conditions	Figures
heart hif1aa expression decreased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart plod2 expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart postnb expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart tgfb3 expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart fn1b expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart col5a1 expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart pcolce2b expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart col1a1a expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart postna expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
whole organism mdka expression decreased amount, abnormal	mdka^cn105/cn105	standard conditions	FIGURE 2 from Grivas et al., 2021
heart fn1a expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart col5a2a expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart cthrc1a expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
cardiac muscle tissue regeneration decreased occurrence, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 3 from Grivas et al., 2021
heart col1a2 expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart col1a1b expression increased amount, abnormal	mdka^cn105/cn105	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021
heart mdka expression amount, ameliorated	mdka^cn105/+	cryoablation: cardiac ventricle	FIGURE 2 from Grivas et al., 2021
endothelial cell proliferation decreased occurrence, abnormal	mdka^cn105/cn105; y1Tg	cryoablation: cardiac ventricle	FIGURE 4 from Grivas et al., 2021

Citations