CRISPR

CRISPR1-glo1

ID
ZDB-CRISPR-191021-1
Name
CRISPR1-glo1
Previous Names
None
Target
Sequence
5' - GGACGTTCTCCCGTAGAG - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zf3029 glo1
Expression
Gene expression in Wild Types + CRISPR1-glo1
No data available
Phenotype
Phenotype resulting from CRISPR1-glo1
No data available
Phenotype of all Fish created by or utilizing CRISPR1-glo1
Phenotype Fish Conditions Figures
whole organism aldh9a1a.2 expression increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. S3 from Lodd et al., 2019
liver fatty, abnormal glo1zf3029/zf3029 increased food availability Fig. 6 from Lodd et al., 2019
whole organism increased weight, abnormal glo1zf3029/zf3029 increased food availability Fig. 6 from Lodd et al., 2019
blood glucose increased amount, abnormal glo1zf3029/zf3029 food availability Fig. 5 from Lodd et al., 2019
fatty acid metabolic process process characteristic, abnormal glo1zf3029/zf3029 standard conditions Fig. 4 from Lodd et al., 2019
whole organism glo1 expression absent, abnormal glo1zf3029/zf3029 standard conditions Fig. 1 from Lodd et al., 2019
liver ab6-rps6k labeling decreased amount, abnormal glo1zf3029/zf3029 increased food availability Fig. 9 from Lodd et al., 2019
glucose metabolic process delayed, abnormal glo1zf3029/zf3029 food availability Fig. 5 from Lodd et al., 2019
liver lipid droplet increased amount, abnormal glo1zf3029/zf3029 increased food availability Fig. 6 from Lodd et al., 2019
whole organism aldh3a1 expression increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. S3 from Lodd et al., 2019
glucose homeostasis disrupted, abnormal glo1zf3029/zf3029 feeding regime Fig. 5 with image from Li et al., 2026
whole organism saturated fatty acid increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. 4 from Lodd et al., 2019
whole organism aldh9a1b expression increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. S3 from Lodd et al., 2019
blood glucose increased amount, abnormal glo1zf3029/zf3029 increased food availability Fig. 6 from Lodd et al., 2019
whole organism aldh3a2a expression increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. S3 from Lodd et al., 2019
skeletal muscle ab6-rps6k labeling increased amount, abnormal glo1zf3029/zf3029 food availability Fig. 9 from Lodd et al., 2019
whole organism lactoylglutathione lyase activity arrested, abnormal glo1zf3029/zf3029 standard conditions Fig. 1 from Lodd et al., 2019
liver ab6-rps6k labeling increased amount, abnormal glo1zf3029/zf3029 food availability Fig. 9 from Lodd et al., 2019
eye methylglyoxal increased amount, abnormal glo1zf3029/zf3029 food availability Fig. 8 from Lodd et al., 2019
blood glucose increased amount, abnormal glo1zf3029/zf3029 feeding regime Fig. 5 with image from Li et al., 2026
whole organism methylglyoxal increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. 1 with image from Li et al., 2026
Fig. 1,  Fig. 5 from Lodd et al., 2019
whole organism omega-9 fatty acid increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. 4 from Lodd et al., 2019
whole organism omega-3 fatty acid increased amount, abnormal glo1zf3029/zf3029 standard conditions Fig. 4 from Lodd et al., 2019
intersegmental vessel morphology, abnormal glo1zf3029/zf3029; y1Tg chemical treatment: methylglyoxal Fig. 2 from Lodd et al., 2019
blood vessel morphology, abnormal glo1zf3029/zf3029; y1Tg chemical treatment: methylglyoxal Fig. 2 from Lodd et al., 2019
blood vessel increased branchiness, abnormal glo1zf3029/zf3029; y1Tg chemical treatment: methylglyoxal Fig. 2 from Lodd et al., 2019
retina ocular blood vessel increased amount, abnormal glo1zf3029/zf3029; y1Tg increased food availability Fig. 7 from Lodd et al., 2019
whole organism phosphatidylinositol 3-kinase/protein kinase B signal transduction increased magnitude, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
whole organism gck expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism ins expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
whole organism insulin decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 6 with image from Li et al., 2026
kidney col4a4 expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
whole organism ins expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
kidney col4a3 expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
whole organism insrb expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
liver arg1 expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
liver odc1 expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
glucose homeostasis disrupted, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 feeding regime Fig. 5 with image from Li et al., 2026
whole organism imidazolinone increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 2 with image from Li et al., 2026
podocyte podocyte foot increased width, exacerbated glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
whole organism glucose decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
whole organism acrolein increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 1 with image from Li et al., 2026
glomerular basement membrane increased thickness, exacerbated glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
liver insrb expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism slc2a2 expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism insra expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
liver arginine decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 2 with image from Li et al., 2026
kidney lamb1a expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
blood glucose increased amount, exacerbated glo1zf3029/zf3029; akr1a1azf3750/zf3750 feeding regime Fig. 5 with image from Li et al., 2026
whole organism slc2a8 expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
liver asl expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism ugp2a expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
whole organism phosphatidylinositol 3-kinase/protein kinase B signal transduction decreased magnitude, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 6 with image from Li et al., 2026
liver slc7a1a expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism gck expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
whole organism gys1 expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism arginine decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 2 with image from Li et al., 2026
liver slc7a1b expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
liver ins expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism glucose amount, ameliorated glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine, chemical treatment by environment: N(gamma)-nitro-L-arginine methyl ester Fig. 6 with image from Li et al., 2026
kidney lama1 expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
whole organism pkmb expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism insrb expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism methylglyoxal increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 1 with image from Li et al., 2026
muscle phosphatidylinositol 3-kinase/protein kinase B signal transduction decreased magnitude, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 feeding regime Fig. 4 with image from Li et al., 2026
whole organism glucose increased amount, exacerbated glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
whole organism slc2a8 expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
liver gys1 expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
glucose homeostasis disrupted, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
liver phosphatidylinositol 3-kinase/protein kinase B signal transduction decreased magnitude, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 feeding regime Fig. 4 with image from Li et al., 2026
whole organism ugp2a expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
whole organism slc2a2 expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
whole organism insulin amount, ameliorated glo1zf3029/zf3029; akr1a1azf3750/zf3750 chemical treatment by environment: arginine Fig. 6 with image from Li et al., 2026
kidney col4a5 expression increased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 5 with image from Li et al., 2026
liver ass1 expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
liver insra expression decreased amount, abnormal glo1zf3029/zf3029; akr1a1azf3750/zf3750 standard conditions Fig. 4 with image from Li et al., 2026
Citations
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