CRISPR

CRISPR1-mipb

ID

ZDB-CRISPR-181017-5

Name

CRISPR1-mipb

Previous Names

None

Target

mipb (1)

Sequence

5' - GGGGGCCATGGCAGGAGCCG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ir1091	mipb

Expression

Gene expression in Wild Types + CRISPR1-mipb

No data available

Phenotype

Phenotype resulting from CRISPR1-mipb

No data available

Phenotype of all Fish created by or utilizing CRISPR1-mipb

Phenotype	Fish	Conditions	Figures
lens fiber cell mipb expression absent, abnormal	mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 1 , Fig. 5 from Vorontsova et al., 2018
lens central region refractivity, abnormal	mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 2 from Vorontsova et al., 2018
lens opacity, abnormal	mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 8 from Wang et al., 2021
lens lens development in camera-type eye decreased process quality, abnormal	mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 2 from Vorontsova et al., 2018
lens central region opaque, abnormal	mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 2 from Vorontsova et al., 2018
lens decreased diameter, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 1 from Wang et al., 2021
lens central region refractivity, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 2 from Vorontsova et al., 2018
lens anterior region opaque, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 3 from Vorontsova et al., 2018
lens fiber cell lens fiber cell morphogenesis decreased process quality, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 7 from Vorontsova et al., 2018
lens lens morphogenesis in camera-type eye decreased process quality, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 6 from Vorontsova et al., 2018
lens opacity, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 9 , Fig. 10 from Wang et al., 2021
lens opaque, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 3 from Vorontsova et al., 2018
lens refractivity, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 4 , Fig. 5 from Wang et al., 2021 Fig. 4 from Vorontsova et al., 2018
lens lens development in camera-type eye decreased process quality, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 2 , Fig. 3 , Fig. 4 from Vorontsova et al., 2018
lens central region opaque, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 2 , Fig. 4 from Vorontsova et al., 2018
lens malformed, abnormal	mipa^{ir1090/ir1090}; mipb^{ir1091/ir1091} (AB)	standard conditions	Fig. 6 from Vorontsova et al., 2018

Citations