ZFIN ID: ZDB-GENE-050706-86
Gene Name: major intrinsic protein of lens fiber b
Gene Symbol: mipb
Sequence Ontology ID : SO:0000704

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Previous Names: mip2, aqp0b (1), zgc:110015

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 5 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12858 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH mipb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cataract 15 multiple types Cataract 15, multiple types 615274
    DISEASE ASSOCIATED WITH mipb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lens development in camera-type eye (more)
    Cellular Component integral component of membrane (more)
    Molecular Function NOT water channel activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000425 (1)
  • InterPro:IPR022357 (1)
  • InterPro:IPR023271 (1)
  • InterPro:IPR034294 (1)
  • PROSITE:PS00221 (1)
  • Pfam:PF00230 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mipb-001 (1) 2138
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mipb No data available
    MARKER RELATIONSHIPS
    mipbContained in: [BAC] CH211-147F12 (1) (order this)
    mipbEncodes: [cDNA] MGC:110015 (1) (order this), MGC:173554 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020520 (1) 2146bp
    Genomic GenBank:CR450824 (1) 170611bp
    Select Tool
    Polypeptide UniProtKB:A9JRM7 (1) 263aa
    Sequence Clusters UniGene:87423 (1)
    Sequence Information (all 18)
    OTHER mipb GENE PAGES
  • Alliance (1)
  • Gene:553420 (1)
  • VEGA:OTTDARG00000021068 (1)
  • Ensembl(GRCz11):ENSDARG00000013963 (1)
  • ORTHOLOGY for mipb (Chr: 23)
    CITATIONS (28)