CRISPR

CRISPR1-sox3

ID

ZDB-CRISPR-180705-3

Name

CRISPR1-sox3

Previous Names

None

Target

sox3 (1)

Sequence

5' - ACGACCAGGACCGGGTGAAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
x52	sox3
x53	sox3

Expression

Gene expression in Wild Types + CRISPR1-sox3

No data available

Phenotype

Phenotype resulting from CRISPR1-sox3

No data available

Phenotype of all Fish created by or utilizing CRISPR1-sox3

Phenotype	Fish	Conditions	Figures
otic placode pax2a expression decreased distribution, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 3 from Gou et al., 2018
vagal ganglion 1 phox2a expression decreased distribution, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
otic placode sox2 expression increased amount, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 2 from Gou et al., 2018
vagal ganglion 1 phox2a expression spatial pattern, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
vagal ganglion 2 phox2a expression decreased amount, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
statoacoustic (VIII) ganglion neuron decreased amount, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 2 from Gou et al., 2018
otic placode sox2 expression increased distribution, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 2 from Gou et al., 2018
otic placode pax8 expression decreased distribution, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 3 from Gou et al., 2018
vagal ganglion 2 phox2a expression spatial pattern, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
facial ganglion phox2a expression absent, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
glossopharyngeal ganglion phox2a expression absent, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
vagal ganglion 2 phox2a expression decreased distribution, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
otic vesicle decreased size, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 1 from Gou et al., 2018
vagal ganglion 1 phox2a expression decreased amount, abnormal	sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
vagal ganglion 1 phox2a expression decreased amount, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
vagal ganglion 1 phox2a expression spatial pattern, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
glossopharyngeal ganglion phox2a expression decreased distribution, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
epibranchial placode pax2a expression decreased amount, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
otic placode pax2a expression decreased distribution, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 3 from Gou et al., 2018
auditory receptor cell decreased amount, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 2 from Gou et al., 2018
vagal ganglion 1 phox2a expression decreased distribution, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
glossopharyngeal ganglion phox2a expression spatial pattern, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
vagal ganglion 2 phox2a expression decreased amount, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
statoacoustic (VIII) ganglion neuron decreased amount, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 2 from Gou et al., 2018
epibranchial placode pax2a expression spatial pattern, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
otic placode pax8 expression decreased distribution, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 3 from Gou et al., 2018
vagal ganglion 2 phox2a expression spatial pattern, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
epibranchial placode pax2a expression decreased distribution, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
vagal ganglion 2 phox2a expression decreased distribution, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
facial ganglion phox2a expression decreased distribution, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
facial ganglion phox2a expression decreased amount, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
glossopharyngeal ganglion phox2a expression decreased amount, abnormal	sox2^x50/x50; sox3^x52/x52 (AB)	standard conditions	Fig. 4 from Gou et al., 2018
otic placode pax2a expression decreased distribution, abnormal	sox3^x52/x52; pax8^{nia03Gt/nia03Gt} (AB)	standard conditions	Fig. 5 from Gou et al., 2018
otic placode pax2a expression decreased amount, abnormal	sox3^x52/x52; pax8^{nia03Gt/nia03Gt} (AB)	standard conditions	Fig. 5 from Gou et al., 2018

Citations