CRISPR

CRISPR1-cxcr4a

ID

ZDB-CRISPR-180412-1

Name

CRISPR1-cxcr4a

Previous Names

None

Target

cxcr4a (1)

Sequence

5' - GGACATCGGAGCCAACTTTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
a169	cxcr4a
y612	cxcr4a

Expression

Gene expression in Wild Types + CRISPR1-cxcr4a

No data available

Phenotype

Phenotype resulting from CRISPR1-cxcr4a

No data available

Phenotype of all Fish created by or utilizing CRISPR1-cxcr4a

Phenotype	Fish	Conditions	Figures
endoderm cell migration involved in gastrulation process quality, abnormal	cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
endoderm sox17 expression decreased distribution, abnormal	cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
endoderm sox17 expression spatial pattern, abnormal	cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
dorsal aorta increased width, abnormal	cxcr4a^y612/y612; p151Tg; y171Tg	standard conditions	Fig. 2 from Stratman et al., 2020
dorsal aorta vascular associated smooth muscle cell decreased amount, abnormal	cxcr4a^y612/y612; p151Tg; y171Tg	standard conditions	Fig. 2 from Stratman et al., 2020
endoderm sox17 expression decreased distribution, abnormal	apela^a141/a141; cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
endoderm cell migration involved in gastrulation process quality, abnormal	apela^a141/a141; cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
blastoderm fn1a expression spatial pattern, abnormal	apela^a141/a141; cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
endoderm sox17 expression spatial pattern, abnormal	apela^a141/a141; cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
mesodermal cell migration decreased process quality, abnormal	apela^a141/a141; cxcr4a^a169/a169	standard conditions	Fig. 7 from Norris et al., 2017
endoderm cell migration involved in gastrulation process quality, abnormal	cxcr4a^a169/a169; apela^a142/a142	standard conditions	Fig. 7 from Norris et al., 2017
endoderm sox17 expression decreased distribution, abnormal	cxcr4a^a169/a169; apela^a142/a142	standard conditions	Fig. 7 from Norris et al., 2017
blastoderm fn1a expression spatial pattern, abnormal	cxcr4a^a169/a169; apela^a142/a142	standard conditions	Fig. 7 from Norris et al., 2017
endoderm sox17 expression spatial pattern, abnormal	cxcr4a^a169/a169; apela^a142/a142	standard conditions	Fig. 7 from Norris et al., 2017
mesodermal cell migration decreased process quality, abnormal	cxcr4a^a169/a169; apela^a142/a142	standard conditions	Fig. 7 from Norris et al., 2017

Citations