Genomic Feature
zf2164
- ID
- ZDB-ALT-190910-3
- Name
- zf2164
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 20: 26377686 - 26377693 (GRCz11) (1) Details
- Nucleotide change
- CACACGAC/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 8 bp deleted in Exon 3 (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
ACAAATAAAATACTTTTTAAAACAAAACCCCCACCACCAATGTAAAATTCATGATATCTACTTTTGATTTGTATTGTATGAGCAAGATGAAACGTGCAATCTATTGTTGTGAATAAACTGTCAAACCCAAAAAGTTAAGGTAACATTTGCAGAAGTTTGCGTAAACCGATTCCAACAAACAATTTAAGTTTCAAAGCTAATCCTTCCTCCATTTAAGTTAAAGAAATGAAGTATTTATTTAACTCATTACTTTCAACACTGAGTTCAAAACTCTTTTCAAATGCGTAGAATTACCTTTCAGTATGTTTTAAGTCAGCTACAGTCATTTCATTTGATAAAGTTGACTGTTGGGTTTTACAGTGTATTAACAAAGCTGTGATTTGTTTTTGTTTTTTATTTGCAGCCGCGTCACATCCCTGCTGATATTCAGAACAACAAGACTGCATGTAAAACAGGCTGGTCACCTTGAATGCTTCTCTTGAAGAAAGCTTTGCATCCCT
CACACGAC/- CAGACTCCGTAATGATATCCAGAGGCGTAGTCACTGCACACCGCACAGAAGCGAGTCTCTTTCCCTGAATCAAAGCCTCCAGCCGCTCTGGATCCAGTGTACAACTCCTGCCTGTCAGTGGCACTGCACAGCTCCTCACACAGGCCCACGGCTGCCTGCTGAGAGGACACCACACTGGACCTGCACAAAAACAGAGGTGAACAGTCAATACACTAGATGTTACACTTCATATAAATAATTATTAAAGCAATAGTATTTAAAGTCTATATGAACATGAGGAGGGTGGCGTTTTATTTTAGCACTCCTCCTAGTCATCTCTCACATCTCAAACTAGATTATAATTGTAAATCAGGTTATAAATAAGAGGAAATAAGCATGCGCAAAAAATAGTAACAGCGTTCGCATGGGTTTCCTCCGGGTGCTCTGGTTTCCCCCACAGTCCAAAGACATGCAGTACAGGTGAATTGGGTTGGCTACATTGTCCATAGTATATGAGTGTG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| esr1zf2164/zf2164 | Homozygous | Unknown | 4 figures  from Chen et al., 2018 | 3 figures from Chen et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Li, X., Wang, L., Qin, X., Chen, X., Li, L., Huang, Z., Zhang, W., Liu, W. (2022) Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models. Cell death discovery. 8:323
- Chen, Y., Tang, H., He, J., Xi, W., Le, W., Liu, X., Lin, H. (2019) Interaction of nuclear ERs and GPER in vitellogenesis in zebrafish. The Journal of steroid biochemistry and molecular biology. 189:10-18
- Chen, Y., Tang, H., Wang, L., He, J., Guo, Y., Liu, Y., Liu, X., Lin, H. (2018) Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish.. Frontiers in endocrinology. 9:567
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