Genomic Feature
bns19
- ID
- ZDB-ALT-180608-2
- Name
- bns19
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Stainier Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 18: 37355109 - 37355149 (GRCz11) (1) Details
- Nucleotide change
- TGGCAGCTTTCTCAACCTCATCGGCACGGAAGGGGGGACGA/-
- Variant Notes
-
p.Ile39Argfs*72
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 41 bp deleted in Exon 1 (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
GAATCATTCAGACAGCCCACTCGAATGTACAATCTATCAACCTAACGATTATTTGTGCTGTGTAGTTTAGTTTGCATAACACTGACTAATACTTTGTAAGGTAGTATGACTTTAGGTTCAGACTTTATTTTACATTTCTTAATTACAAATCAAGAATGACATTTCACTTTTATTTGACTATTTATGACTTTCAGTAATATGCAATCGGCCTTTATTTTCCTGCATAAATGTATCTCTAAATACGATGTTTACAGTTCTTTAAGCATGCAAAAACAAACAAATAAAACTAATAAAAATATTTTAAATCTGTGACTGTGTCATTACAAACTATACGAAAATACTACGCAGTGACACTGCAGGCTGAAAGTGTGCATTGCCCCGGCGCCAGTTGCAGTGTCAGGCGCAGGAAAAGTTTGTGGAAACTGTTTGTGGTTTCTGAGGGGGTGGTCTCTTACTTGTCTGGAGTGGGACTTTGGCTCTGGCGGCGTGAAGAATGAGTC
TGGCAGCTTTCTCAACCTCATCGGCACGGAAGGGGGGACGA/- TGGTGTTTTTCGGGTTCATCACAGCGTTAAAAAGAGCCTCCAGATCGGTCTCGGAGTCTCCCCGAACATGGACGATCTGGTGGCCGGCTGGAGGGTTGTGCTGGTTCGGATCCATGACTCCAGATAAAAGTAAAACTCTTCTTTCTATCCAACTGAAACCGTTTTCAAGGAAAGTCGGCTGCAACCATACAAATGGCGAAAATTTTAATCCAAAACAACCCAAAAAGATGTTCTGTGTCCGGCCGCTTTATCAATTATCCAAGCCTTGCGAAGGAAAAAAATTGGCAACGTTGTGTTTTGCTGCTTGCCAAAAACACCCAAATAAATGTGGAAACGCGCATATCTACAAAACTGTATCTCTAAAACTTTTTCTAAGGTGTCTAAACTTTCTAAAATCGTTGTCTGTGTTGCTTTTCCAGTAGTTTACGGCTCTTCTAACGCAGGCATTGGTAGTGACTGTACTGCGCATTGAAAATCACAGCCCTCTCACTAACCTAACT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| yap1bns19/bns19 | Homozygous | ♀+/- ♂+/- | Fig. 2  from Kimelman et al., 2017 | ||
| yap1bns19/bns19; ci1Tg | Complex | Fig. S8 from Astone et al., 2018 | |||
| yap1bns19/bns19; wwtr1bns35/bns35 | Complex | 7 figures from Kimelman et al., 2017 | 3 figures from Kimelman et al., 2017 | ||
| yap1bns19/bns19; wwtr1bns35/+ | Complex | Fig. 5 from Astone et al., 2018 | Fig. 5 from Astone et al., 2018 | ||
| yap1bns19/bns19; wwtr1bns35/+; ci1Tg; nz101Tg | Complex | Fig. 5 from Astone et al., 2018 |
1 - 5 of 5
Show
Supplemental Information
- Genotyping protocol
- None
- Lee, S.H., So, J., Shin, D. (2023) Hepatocyte-to-cholangiocyte conversion occurs through transdifferentiation independently of proliferation in zebrafish. Hepatology (Baltimore, Md.). 77(4):1198-1210
- Lai, J.K.H., Toh, P.J.Y., Cognart, H.A., Chouhan, G., Saunders, T.E. (2022) DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells. eLIFE. 11:
- Brandão, A.S., Bensimon-Brito, A., Lourenço, R., Borbinha, J., Soares, A.R., Jacinto, A. (2019) Yap induces osteoblast differentiation by modulating Bmp signalling during zebrafish caudal fin regeneration. Journal of Cell Science. 132(22):
- Astone, M., Lai, J.K.H., Dupont, S., Stainier, D.Y.R., Argenton, F., Vettori, A. (2018) Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Scientific Reports. 8:10189
- Kimelman, D., Smith, N.L., Lai, J.K.H., Stainier, D.Y. (2017) Regulation of posterior body and epidermal morphogenesis in Zebrafish by localized Yap1 and Wwtr1. eLIFE. 6
1 - 5 of 5
Show