Genomic Feature
f19
- ID
- ZDB-ALT-160901-16
- Name
- f19
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one insertion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Randall Peterson Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Insertion
- Variant Location
- Chr 10: 14490987 - 14490988 (GRCz11) (1) Details
- Nucleotide change
- -/ATCATGATCATGAGCAGGCCTTCTC
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 25 bp inserted (1)
- Transcript Consequence
- Frameshift (1)
- Protein Consequence
- None
- Flanking Sequence
-
TTCTTTCATCATTTGCAGTGTTTGGTTATTTCTATTTTTATTTGTTTTATCTATTTTCTGTAAAGCTGCTTCTGACCATGACACTCCACTCCTAAATGGCTATAAGAGAAATGTTTAAGAGATAATATGCAGCATCTTTAATTTATTCTCTTAGGTTAGGAGAGATCTTCACTTAAGTATCATACTTAGAGGAAAAAAGTATTTTATGCTTAAAGCATCCGAAATGGTACAATATATCGGCCGATCACCGTGACAAGGAATGGGTACCTGGTATTGGTTGCAAAAATCCTGAACGGAGCATCCCGAATCTGATTTAATTTATTTGTATGAACTCAAAAATTATCATTTTGTTTATTTTATTCATAATCATTCAAAATGTCAAAAGTTTAAAAAGTAGGTAATCTTGATATATCATGTGCTGTGCACTATAGAAGCTGGTGTCTGAATGCTCTAAATTTGTGTTTATAGGTCAGGATCATGAGCAGGCCTTCTCTAAGGTGG
-/ATCATGATCATGAGCAGGCCTTCTC TTGTGGAGCTGCGCAGGAGGTACCCAGGTCACATCCTTCCTGACGAGGACCTGCAGTGGGTGTTTGTAAATGCGGGTGGCTGGATGGGCTCCATGTGTCTCCTGCACGCCTCGCTCACTGAGTATGTGCTGCTGTTCGGGACAGCGGTGGACACCGGTGGACATTCAGGTCATAATAGTTTCATAATCTGCATACTGTATTTCCATTTTGAATTAGTTTGGGTATCTGTATAACTACACGTATACTTATTCAAACTATTAATTTGTGTTGTTGTGATTCACATATATTTTTTTATTTGTTTTACTATATAGTTTACTATTGTTTAGCTTTTTTTTAATATTTTAGATTTGAAACTATATTGTATTCAAACAGCAACTTCTCTTTAATAAGTGCAGTGAAGAAATGTCAAGGTTTTAAATAATAATAATAATAATTAAAAAAGGGAATAAAGTCATACAATATAATACCTAAAACAGGCCTAATTGTCTATATTGTGAAGTT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| sigmar1f19/f19 | Homozygous | Unknown | Fig. S20 from Rennekamp et al., 2016 | ||
| sigmar1f19/f19 | Homozygous | ♀+/- ♂+/- | 4 figures  from Crouzier et al., 2021 | 3 figures from Crouzier et al., 2021 |
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Supplemental Information
- Genotyping protocol
- None
- Crouzier, L., Denus, M., Richard, E.M., Tavernier, A., Diez, C., Cubedo, N., Maurice, T., Delprat, B. (2021) Sigma-1 Receptor Is Critical for Mitochondrial Activity and Unfolded Protein Response in Larval Zebrafish. International Journal of Molecular Sciences. 22(20):
- Rennekamp, A.J., Huang, X.P., Wang, Y., Patel, S., Lorello, P.J., Cade, L., Gonzales, A.P., Yeh, J.J., Caldarone, B.J., Roth, B.L., Kokel, D., Peterson, R.T. (2016) σ1 receptor ligands control a switch between passive and active threat responses. Nature Chemical Biology. 12(7):552-8
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