Genomic Feature
sus002
- ID
- ZDB-ALT-150416-3
- Name
- sus002
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- The Wang Laboratory
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 2: 48356336 - 48356346 (GRCz11) (1) Details
- Nucleotide change
- TGCTGAGTCCT/-
- Variant Notes
-
11-bp deletion
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 11 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
ATGGCCATATAAAAATTAAATAAAATTAACATAAAATAAATTTAATAAAAAGGCCACATAAAAATTAAATAAAATAAAATGATTAATTTAAATTTAAATTTAAATAAAATAAAAAACGTTAACAATTAATACAATTCATAATTAATACTAAAAATAACACTGACATAAAAAGGAAAGGATATGGCTTACTAACAAAACTAAATATATACCATAGCGACACATTAAATAAAATACAATAAAAAATTTAATAAAATGAACCAAAATAAGCCATCAGGTCTCAACTGTTTGTCATGATTGCCATTGAATTACAAAATCAGGCGACACAAGCTGACTTTTTTTAAAGAAGTTTGCTAGTTATGCTCATAAACCAAAAGATACCATACTATGCAAAACAGAGAGCATCCTTATGCTTACTCTGCCTTGATGACCGTGTTCAAATACTATTTAGTCTTACTGAAAATCACAAATTACCTCTTGTTGCTTCCCGATGACACCAGTAG
TGCTGAGTCCT/- TGCTTCGGCTATTGGAACTCCCAGAAGACTCATTGCCATGAGATTCATTTCCGTGGGATTCATTACCATGAGACTCATTGCCATGAGACTCTGTTCCGCTCCCGCTGGACCCGCTGCTACTCTTCATCTCCACATCCTCATGTAGGGAATGACTCATCTTCCGGGTGTTGTGGCCCGAGGTTGGACGGTCCTGGCTGCTGTCGCTGCCTTCAGATGCCAGGCCCAGTTCAGTGCCTTCTGCGAAACTGGCCATACGATGAAGCGTCGCCATTGAGCTGCAGCCGATTGCTCCGTCCTGCCCCTCCAAGGAGGAGAACAAGTACGGTTTGGAATCCAGGTCTTTAGACATCGGACTTGGGTTTAATGTTGTGAAGTAAAACACGAACAAATCACCCCATCCTCATGGTGGGTCCACTGAGAGAATGCAGACGGACACTCGGATTTCTGTGGGAATAAAAATAGAAAGAGCATGAGAATGGTCCACAAAAAGTTCAGACATT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| per2sus002/sus002 | Homozygous | ♀+/- ♂+/- | 4 figures  from 2 publications | 5 figures from 2 publications | |
| per2sus002/sus002 | Homozygous | Unknown | 2 figures from Ren et al., 2018 | ||
| per2sus002/sus002; nz117Tg | Complex | Fig. 4 from Ren et al., 2018 | |||
| per2sus002/sus002; sus008Tg | Complex | ||||
| per2sus002/sus002; sus009Tg | Complex |
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Supplemental Information
- Genotyping protocol
- None
- Chen, A.Q., Xue, M., Qiu, C.Z., Zhang, H.Y., Zhou, R., Zhang, L., Yin, Z.J., Ren, D.L. (2023) Circadian clock1a coordinates neutrophil recruitment via nfe212a/duox-reactive oxygen species pathway in zebrafish. Cell Reports. 42:113179113179
- Huang, D.F., Wang, M.Y., Yin, W., Ma, Y.Q., Wang, H., Xue, T., Ren, D.L., Hu, B. (2018) Zebrafish Lacking Circadian Gene per2 Exhibit Visual Function Deficiency.. Frontiers in behavioral neuroscience. 12:53
- Ren, D.L., Zhang, J.L., Yang, L.Q., Wang, X.B., Wang, Z.Y., Huang, D.F., Tian, C., Hu, B. (2018) Circadian genes period1b and period2 differentially regulate inflammatory responses in zebrafish. Fish & shellfish immunology. 77:139-146
- Wang, M., Zhong, Z., Zhong, Y., Zhang, W., Wang, H. (2015) The Zebrafish Period2 Protein Positively Regulates the Circadian Clock through Mediation of Retinoic Acid Receptor (RAR)-related Orphan Receptor α (Rorα). The Journal of biological chemistry. 290(7):4367-4382
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