ZFIN Lab: Cui Lab

ZFIN ID: ZDB-LAB-131112-1

Cui Lab

PI/Director:	Cui, Zongbin
Co-PI / Senior Researcher:	Long, Yong
Contact Person:	Cui, Zongbin
Email:	zbcui@ihb.ac.cn
URL:
Address:	Institute of Hydrobiology, Chinese Academy of Sciences 7# South Donghu Rd, Wuhan 430072, Hubei, P.R.China
Country:	China
Phone:	86-27-68780090
Fax:
Line Designation:	ihb

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 37 genomic features

STATEMENT OF RESEARCH INTERESTS

Insertional mutagenesis in zebrafish; Mechanisms underlying the cold acclimation of fish; Intracellular signaling regulation during normal embryonic development of zebrafish

LAB MEMBERS

Chen, Kai Graduate Student	Li, Xiaohui Graduate Student	Li, Xixi Graduate Student
Yan, Junjun Graduate Student	Zhou, Bolan Graduate Student	Li, Qing Research Staff
Song, Guili Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Ge, G., Ren, J., Song, G., Li, Q., Cui, Z. (2023) Transcriptome Analysis Reveals the Molecular Basis of Overfeeding-Induced Diabetes in Zebrafish. International Journal of Molecular Sciences. 24(15):

Hu, H., Long, Y., Song, G., Chen, S., Xu, Z., Li, Q., Wu, Z. (2023) Dysfunction of Prkcaa Links Social Behavior Defects with Disturbed Circadian Rhythm in Zebrafish. International Journal of Molecular Sciences. 24(4):

Li, X., Ge, G., Song, G., Li, Q., Cui, Z. (2023) Effects of Nutritionally Induced Obesity on Metabolic Pathways of Zebrafish. International Journal of Molecular Sciences. 24(3):

Wang, C., Wang, B., Pandey, T., Long, Y., Zhang, J., Oh, F., Sima, J., Guo, R., Liu, Y., Zhang, C., Mukherjee, S., Bassik, M., Lin, W., Deng, H., Vale, G., McDonald, J.G., Shen, K., Ma, D.K. (2022) A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience. Nature communications. 13:6805

Liu, R., Long, Y., Liu, R., Song, G., Li, Q., Yan, H., Cui, Z. (2022) Understanding the Function and Mechanism of Zebrafish Tmem39b in Regulating Cold Resistance. International Journal of Molecular Sciences. 23(19):

Zhao, Y., Li, X., Song, G., Li, Q., Yan, H., Cui, Z. (2022) Comparative Transcriptome Analysis Provides Novel Molecular Events for the Differentiation and Maturation of Hepatocytes during the Liver Development of Zebrafish. Biomedicines. 10(9)

Ge, G., Long, Y., Song, G., Li, Q., Cui, Z., Yan, H. (2022) Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress. International Journal of Molecular Sciences. 23(14):

Li, X., Song, G., Zhao, Y., Ren, J., Li, Q., Cui, Z. (2021) Functions of SMC2 in the Development of Zebrafish Liver. Biomedicines. 9(9):

Li, F., Long, Y., Xie, J., Ren, J., Zhou, T., Song, G., Li, Q., Cui, Z. (2021) Generation of GCaMP6s-Expressing Zebrafish to Monitor Spatiotemporal Dynamics of Calcium Signaling Elicited by Heat Stress. International Journal of Molecular Sciences. 22(11):

Ren, J., Long, Y., Liu, R., Song, G., Li, Q., Cui, Z. (2021) Characterization of Biological Pathways Regulating Acute Cold Resistance of Zebrafish. International Journal of Molecular Sciences. 22(6):

Lu, X., Long, Y., Li, X., Zhang, L., Li, Q., Wen, H., Zhong, S., Cui, Z. (2021) Generation of Knockout and Transgenic Zebrafish to Characterize Abcc4 Functions in Detoxification and Efflux of Lead. International Journal of Molecular Sciences. 22(4):

Zhou, T., Zhou, B., Zhao, Y., Li, Q., Song, G., Zhu, Z., Long, Y., Cui, Z. (2021) Development of a Mucus Gland Bioreactor in Loach Paramisgurnus dabryanus. International Journal of Molecular Sciences. 22(2):

Long, Y., Liu, R., Song, G., Li, Q., Cui, Z. (2020) Establishment and characterization of a cold-sensitive neural cell line from the brain of tilapia (Oreochromis niloticus). Journal of Fish Biology. 98(3):842-854

Zhang, L., Fang, Y., Lu, X., Xu, S., Cai, F., Yu, M., Li, X., Zhong, S. (2020) Transcriptional response of zebrafish larvae exposed to lindane reveals two detoxification genes of ABC transporter family (abcg5 and abcg8). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 232:108755

Ren, F., Lin, Q., Gong, G., Du, X., Dan, H., Qin, W., Miao, R., Xiong, Y., Xiao, R., Li, X., Gui, J.F., Mei, J. (2020) Igf2bp3 maintains maternal RNA stability and ensures early embryo development in zebrafish. Communications biology. 3:94

Yan, J., Long, Y., Zhou, T., Ren, J., Li, Q., Song, G., Cui, Z. (2019) Dynamic Phosphoproteome Profiling of Zebrafish Embryonic Fibroblasts During Cold Acclimation. Proteomics. 20(2):e1900257

Yang, X., Li, X., Gu, Q., Li, Q., Cui, Z. (2019) Nucleoporin 62-Like Protein is Required for the Development of Pharyngeal Arches through Regulation of Wnt/β-Catenin Signaling and Apoptotic Homeostasis in Zebrafish. Cells. 8(9):

Chen, K., Li, X., Song, G., Zhou, T., Long, Y., Li, Q., Zhong, S., Cui, Z. (2019) Deficiency in the membrane protein Tmbim3a/Grinaa initiates cold-induced ER stress and cell death by activating an intrinsic apoptotic pathway in zebrafish. The Journal of biological chemistry. 294(30):11445-11457

Li, D., Xue, W., Li, M., Dong, M., Wang, J., Wang, X., Li, X., Chen, K., Zhang, W., Wu, S., Zhang, Y., Gao, L., Chen, Y., Chen, J., Zhou, B.O., Zhou, Y., Yao, X., Li, L., Wu, D., Pan, W. (2018) VCAM-1⁺ macrophages guide the homing of HSPCs to a vascular niche. Nature. 564(7734):119-124

Chen, T., Song, G., Yang, H., Mao, L., Cui, Z., Huang, K. (2018) Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish. Genetics. 208(3):1131-1146

Wu, D.M., Ma, L.P., Song, G.L., Long, Y., Liu, H.X., Liu, Y., Ping, J. (2017) Steroidogenic factor-1 hypermethylation in maternal rat blood could serve as a biomarker for intrauterine growth retardation. Oncotarget. 8:96139-96153

Ma, Z., Zhu, P., Pang, M., Guo, L., Chang, N., Zheng, J., Zhu, X., Gao, C., Huang, H., Cui, Z., Xiong, J.W., Peng, J., Chen, J. (2017) A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants. Scientific Reports. 7:10381

Li, X., Song, G., Zhao, Y., Zhao, F., Liu, C., Liu, D., Li, Q., Cui, Z. (2017) Claudin7b is required for the formation and function of inner ear in zebrafish. Journal of Cellular Physiology. 233(4):3195-3206

Xue, T., Yu, M., Pan, Q., Wang, Y., Fang, J., Li, L., Deng, Y., Chen, K., Wang, Q., Chen, T. (2017) Black carp vasa identifies embryonic and gonadal germ cells. Development genes and evolution. 227(4):231-243

Zhai, G., Song, J., Shu, T., Yan, J., Jin, X., He, J., Yin, Z. (2017) LRH-1 senses signaling from phosphatidylcholine to regulate the expansion growth of digestive organs via synergy with Wnt/β-catenin signaling in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 44(6):307-317

Zhang, C.H., Chen, K., Jiao, Y., Li, L.L., Li, Y.P., Zhang, R.J., Zheng, M.W., Zhong, L., Huang, S.Z., Song, C.L., Lin, W.T., Yang, J., Xiang, R., Peng, B., Han, J.H., Lu, G.W., Wei, Y.Q., Yang, S.Y. (2016) From Lead to Drug Candidate: Optimization of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer. Journal of medicinal chemistry. 59:9788-9805

Zhou, W., He, Q., Zhang, C., He, X., Cui, Z., Liu, F., Li, W. (2016) BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development. eLIFE. 5

Liu, J., Zhu, Y., Luo, G.Z., Wang, X., Yue, Y., Wang, X., Zong, X., Chen, K., Yin, H., Fu, Y., Han, D., Wang, Y., Chen, D., He, C. (2016) Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig. Nature communications. 7:13052

Li, L., Shi, W., Wu, X., Gong, Q., Li, X., Ma, H. (2016) Monitoring γ-glutamyl transpeptidase activity and evaluating its inhibitors by a water-soluble near-infrared fluorescent probe. Biosensors & bioelectronics. 81:395-400

Zheng, M.W., Zhang, C.H., Chen, K., Huang, M., Li, Y.P., Lin, W.T., Zhang, R.J., Zhong, L., Xiang, R., Li, L.L., Liu, X.Y., Wei, Y.Q., Yang, S.Y. (2016) Preclinical evaluation of a novel orally available SRC/Raf/VEGFR2 inhibitor, SKLB646, in the treatment of triple negative breast cancer. Molecular cancer therapeutics. 15(3):366-78

Hu, M., Bai, Y., Zhang, C., Liu, F., Cui, Z., Chen, J., Peng, J. (2016) Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish. PLoS Genetics. 12:e1005881

Li, Z., Long, Y., Zhong, L., Song, G., Zhang, X., Yuan, L., Cui, Z., Dai, H. (2016) RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate. Journal of applied toxicology : JAT. 36(1):94-104

Feng, G., Long, Y., Peng, J., Li, Q., Cui, Z. (2015) Transcriptomic characterization of the dorsal lobes after hepatectomy of the ventral lobe in zebrafish. BMC Genomics. 16:979

Liu, C., Song, G., Mao, L., Long, Y., Li, Q., Cui, Z. (2015) Generation of an Enhancer-Trapping Vector for Insertional Mutagenesis in Zebrafish. PLoS One. 10:e0139612

Long, Y., Yan, J., Song, G., Li, X., Li, X., Li, Q., Cui, Z. (2015) Transcriptional events co-regulated by hypoxia and cold stresses in Zebrafish larvae. BMC Genomics. 16:385

Yang, X., Gu, Q., Lin, L., Li, S., Zhong, S., Li, Q., Cui, Z. (2015) Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish. Molecular and cellular biology. 35(7):1110-24

Safavi-Hemami, H., Gajewiak, J., Karanth, S., Robinson, S.D., Ueberheide, B., Douglass, A.D., Schlegel, A., Imperial, J.S., Watkins, M., Bandyopadhyay, P.K., Yandell, M., Li, Q., Purcell, A.W., Norton, R.S., Ellgaard, L., Olivera, B.M. (2015) Specialized insulin is used for chemical warfare by fish-hunting cone snails.. Proceedings of the National Academy of Sciences of the United States of America. 112(6):1743-1748

Lu, X., Long, Y., Sun, R., Zhou, B., Lin, L., Zhong, S., Cui, Z. (2015) Zebrafish Abcb4 is a potential efflux transporter of microcystin-LR. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 167:35-42

Lu, X., Long, Y., Lin, L., Sun, R., Zhong, S., Cui, Z. (2014) Characterization of Zebrafish Abcc4 as an Efflux Transporter of Organochlorine Pesticides. PLoS One. 9:e111664

Gu, Q., Yang, X., Lin, L., Li, S., Li, Q., Zhong, S., Peng, J., Cui, Z. (2014) Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology (Baltimore, Md.). 60(6):1929-41

Zhong, L., Yuan, L., Rao, Y., Li, Z., Gu, Q., Long, Y., Zhang, X., Cui, Z., Xu, Y., Dai, H. (2014) Investigation of effect of 17α-ethinylestradiol on vigilin expression using an isolated recombinant antibody. Aquatic toxicology (Amsterdam, Netherlands). 156:1-9

Gu, Q., Yang, X., He, X., Li, Q., and Cui, Z. (2013) Generation and characterization of a transgenic zebrafish expressing the reverse tetracycline transactivator. Journal of genetics and genomics = Yi chuan xue bao. 40(10):523-531

Long, Y., Song, G., Yan, J., He, X., Li, Q., and Cui, Z. (2013) Transcriptomic characterization of cold acclimation in larval zebrafish. BMC Genomics. 14(1):612

Wen, R., Li, J., Xu, X., Cui, Z., and Xiao, W. (2012) Zebrafish Mms2 promotes K63-linked polyubiquitination and is involved in p53-mediated DNA-damage response. DNA repair. 11(2):157-166

Long, Y., Li, L., Li, Q., He, X., and Cui, Z. (2012) Transcriptomic characterization of temperature stress responses in larval zebrafish. PLoS One. 7(5):e37209

Song, G., Li, Q., Long, Y., Gu, Q., Hackett, P.B., and Cui, Z. (2012) Effective gene trapping mediated by sleeping beauty transposon. PLoS One. 7(8):e44123

Li, Y., Li, Q., Long, Y., and Cui, Z. (2011) Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear β-Catenin in Zebrafish. The Journal of biological chemistry. 286(52):45116-30

Long, Y., Li, Q., Zhong, S., Wang, Y., and Cui, Z. (2011) Molecular characterization and functions of zebrafish ABCC2 in cellular efflux of heavy metals. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 153(4):381-91

Long, Y., Li, Q., Wang, Y., and Cui, Z. (2011) MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 153(3):310-317

Shang, H., Li, Q., Feng, G., and Cui, Z. (2011) Molecular analysis and functions of p53R2 in zebrafish. Gene. 475(1):30-38

Long, Y., Li, Q., and Cui, Z. (2011) Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish. Molecular biology reports. 38(3):1703-1711

Zou, J., Li, W.Q., Li, Q., Li, X.Q., Zhang, J.T., Liu, G.Q., Chen, J., Qiu, X.X., Tian, F.J., Wang, Z.Z., Zhu, N., Qin, Y.W., Shen, B., Liu, T.X., and Jing, Q. (2011) Two Functional MicroRNA-126s Repress a Novel Target Gene p21-Activated Kinase 1 to Regulate Vascular Integrity in Zebrafish. Circulation research. 108(2):201-209

Long, Y., Li, Q., Li, J., and Cui, Z. (2011) Molecular analysis, developmental function and heavy metal-induced expression of ABCC5 in zebrafish. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 158(1):46-55

Shang, H., Li, Q., Feng, G., and Cui, Z. (2011) Identification and characterization of alternative promoters, transcripts and protein isoforms of zebrafish r2 gene. PLoS One. 6(8):e24089

Li, J., Wen, R., Andersen, P., Liang, Y., Li, Q., Xiao, W., and Cui, Z. (2010) Zebrafish Ubc13 is required for Lys63-linked polyubiquitination and DNA damage tolerance. Molecular and cellular biochemistry. 343(1-2):173-182

Mo, S., Wang, L., Li, Q., Li, J., Li, Y., Thannickal, V.J., and Cui. Z. (2010) Caveolin-1 regulates dorsoventral patterning through direct interaction with beta-catenin in zebrafish. Developmental Biology. 344(1):210-223

Cui, Z., Samuel-Shaker, D., Watral, V., and Kent, M.L. (2010) Attenuated Mycobacterium marinum protects zebrafish against mycobacteriosis. Journal of fish diseases. 33(4):371-375

Zhang, C., Li, Q., and Jiang, Y.J. (2007) Zebrafish Mib and Mib2 Are Mutual E3 Ubiquitin Ligases with Common and Specific Delta Substrates. Journal of molecular biology. 366(4):1115-1128

Cui, Z., Yang, Y., Kaufman, C.D., Agalliu, D., and Hackett, P.B. (2003) RecA-mediated, targeted mutagenesis in zebrafish. Marine biotechnology (New York, N.Y.). 5(2):174-184

Cui, Z., Clark, K.J., Kaufman, C.D., and Hackett, P.B. (2001) Inhibition of skiA and skiB gene expression ventralizes zebrafish embryos. Genesis (New York, N.Y. : 2000). 30(3):149-153