Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-960805-509
Sepich, Diane
Lila Solnica-Krezel Lab
Department of Biological Sciences
Vanderbilt University
VU Station B 351634
Nashville, TN
37235-1634
USA
Phone: (615) 322-4736 Email: diane.s.sepich@vanderbilt.edu
FAX: (615) 343-6707 URL:
Biography and Research Interests:

Publications:
Lin, F., Chen, S., Sepich, D.S., Panizzi, J.R., Clendenon, S.G., Marrs, J.A., Hamm, H.E., and Solnica-Krezel, L. (2009) Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton. J. Cell Biol.. 184(6):909-921
Zeng, X.X., Wilm, T.P., Sepich, D.S., and Solnica-Krezel, L. (2007) Apelin and Its Receptor Control Heart Field Formation during Zebrafish Gastrulation. Dev. Cell. 12(3):391-402
Cha, Y.I., Kim, S.H., Sepich, D., Buchanan, F.G., Solnica-Krezel, L., and Dubois, R.N. (2006) Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes Dev.. 20(1):77-86
Lin, F., Sepich, D.S., Chen, S., Topczewski, J., Yin, C., Solnica-Krezel, L., and Hamm, H. (2005) Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. J. Cell Biol.. 169(5):777-787
Sepich, D.S., Calmelet, C., Kiskowski, M., and Solnica-Krezel, L. (2005) Initiation of convergence and extension movements of lateral mesoderm during zebrafish gastrulation. Dev. Dyn.. 234(2):279-292
Sepich, D.S., and Solnica-Krezel, L. (2004) Analysis of cell movements in zebrafish embryos: morphometrics and measuring movement of labeled cell populations in vivo. Methods Mol. Biol.. 294:211-234
Jessen, J.R., Topczewski, J., Bingham, S., Sepich, D.S., Marlow, F., Chandrasekhar, A., and Solnica-Krezel, L. (2002) Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat. Cell Biol.. 4(8):610-615
Marlow, F., Topczewski, J., Sepich, D., and Solnica-Krezel, L. (2002) Zebrafish rho kinase 2 acts downstream of wnt11 to mediate cell polarity and effective convergence and extension movements. Curr. Biol.. 12(11):876-884
Myers, D., Sepich, D. and Solnica-Krezel, L. (2002) Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity?. Trends Genet.. 18(9):447-455
Myers, D., Sepich, D., and Solnica-Krezel, L. (2002) Bmp activity gradient regulates convergent extension during zebrafish gastrulation. Dev. Biol.. 243(1):81-98
Solnica-Krezel, L., Marlow, F., Topczewski, J., Jessen, J., and Sepich, D. (2002) Regulation of cell polarity during zebrafish gastrulation. Dev. Biol.. 247(2):479
Solnica-Krezel, L., Topczewski, J., Sepich, D., Myers, D., Marlow, F., and Jessen, J. (2001) Genetic control of convergent extension movements during zebrafish gastrulation. Dev. Biol.. 235(1):175 (#17)
Topczewski, J., Sepich, D.S., Myers, D.C., Walker, C., Amores, A., Lele, Z., Hammerschmidt, M., Postlethwait, J., and Solnica-Krezel, L. (2001) The zebrafish glypican Knypek controls cell polarity during gastrulation movements of convergent extension. Dev. Cell. 1(2):251-264
Henry, C.A., Crawford, B.D., Sepich, D., Cooper, M.S., and Hille, M. (2000) Subcellular localization of focal adhesion kinase during zebrafish organogenesis: Distinct roles for FAK in notochord and somite morphogenesis.. Mol. Biol. Cell. 11:297
Sepich, D.S., Myers, D.C., Short, R., Topczewski, J., Marlow, F., and Solnica-Krezel, L. (2000) Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension. Genesis. 27(4):159-173
Sepich, D.S., Wegner, J., O'Shea, S., and Westerfield, M. (1998) An altered intron inhibits synthesis of the acetylcholine receptor alpha-subunit in the paralyzed zebrafish mutant nic1. Genetics. 184:361-372
Sepich, D.S. (1994) Characterizations of the zebrafish acetylcholine receptor mutant, nic1. Ph.D. Thesis, University of Oregon.
Sepich, D.S., Ho, R.K., and Westerfield, M. (1994) Autonomous expression of the nic1 acetylcholine receptor mutation in zebrafish muscle cells. Dev. Biol.. 161:84-90
Kimmel, C.B., Sepich, D.S., and Trevarrow, B. (1988) Development of segmentation in zebrafish. Development. 104:197-208

Non-Zebrafish Publications: