Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-020826-1
Chen, Yau-Hung
Department of Chemistry
Tamkang University
No. 151 Ying-chuan Road
Tamsui, 251
Taiwan
Phone: +886-2-26215656 ext 3009 Email: yauhung@mail.tku.edu.tw
FAX: +886-2-26209924 URL: http://www2.tku.edu.tw/~tscx/2009chinese/teachers/teacher_view.php?id=22
Biography and Research Interests:

Publications:
Chen, Y.H., and Lin, J.S. (2009) A novel zebrafish mutant with wavy-notochord: An effective biological index for monitoring the copper pollution of water from natural resources. Environ. Toxicol.. :
Chen, Y.H., Lin, Y.T., and Lee, G.H. (2009) Novel and unexpected functions of zebrafish CCAAT box binding transcription factor (NF-Y) B subunit during cartilages development. Bone. 44(5):777-784
Chen, Y.H., Wang, Y.H., Yu, T.H., Wu, H.J., and Pai, C.W. (2009) Transgenic zebrafish line with over-expression of Hedgehog on the skin: a useful tool to screen Hedgehog-inhibiting compounds. Transgenic. Res.. 18(6):855-864
Pai, C.W., and Chen, Y.H. (2009) Transgenic expression of prothymosin alpha on zebrafish epidermal cells promotes proliferation and attenuates UVB-induced apoptosis. Transgenic. Res.. :
Chen, Y.H., Huang, F.L., Cheng, Y.C., Wu, C.J., Yang, C.N., and Tsay, H.J. (2008) Knockdown of zebrafish Na(v)1.6 sodium channel impairs embryonic locomotor activities. J. Biomed. Sci.. 15(1):69-78
Chen, Y.H., Huang, Y.H., Wen, C.C., Wang, Y.H., Chen, W.L., Chen, L.C., and Tsay, H.J. (2008) Movement disorder and neuromuscular change in zebrafish embryos after exposure to caffeine. Neurotoxicol. Teratol.. 30(5):440-447
Wang, Y.H., Li, C.K., Lee, G.H., Tsay, H.J., Tsai, H.J., and Chen, Y.H. (2008) Inactivation of zebrafish mrf4 leads to myofibril misalignment and motor axon growth disorganization. Dev. Dyn.. 237(4):1043-1050
Wu, S.H., Chen, Y.H., Huang, F.L., Chang, C.H., Chang, Y.F., and Tsay, H.J. (2008) Multiple regulatory elements mediating neuronal-specific expression of zebrafish sodium channel gene, Scn8aa. Dev. Dyn.. 237(9):2554-2565
Chen, Y.H., Chen, W.L., Wang, Y.H., Huang, M.Y. and Chern, M.K. (2007) Spatiotemporal expression of zebrafish D -amino acid oxidase during early embryogenesis. Fish Physiol. Biochem.. 33(1):73-80
Chen, Y.H., Wang, Y.H., Chang, M.Y., Lin, C.Y., Weng, C.W., Westerfield, M., and Tsai, H.J. (2007) Multiple upstream modules regulate zebrafish myf5 expression. BMC Dev. Biol.. 7(1):1
Tsay, H.J., Wang, Y.H., Chen, W.L., Huang, M.Y., and Chen, Y.H. (2007) Treatment with sodium benzoate leads to malformation of zebrafish larvae. Neurotoxicol. Teratol.. 29(5):562-569
Lee, H.C., Huang, H.Y., Lin, C.Y., Chen, Y.H., and Tsai, H.J. (2006) Foxd3 mediates zebrafish myf5 expression during early somitogenesis. Dev. Biol.. 290(2):359-372
Lin, C.Y., Yung, R.F., Lee, H.C., Chen, W.T., Chen, Y.H., and Tsai, H.J. (2006) Myogenic regulatory factors Myf5 and Myod function distinctly during craniofacial myogenesis of zebrafish. Dev. Biol.. 299(2):594-608
Wang, Y.H., Chen, Y.H., Lin, Y.J., and Tsai, H.J. (2006) Spatiotemporal expression of zebrafish keratin 18 during early embryogenesis and the establishment of a keratin 18:RFP transgenic line. Gene Expr. Patterns. 6(4):335-339
Wang, Y.H., Chen, Y.H., Lu, J.H., Lin, Y.J., Chang, M.Y., and Tsai, H.J. (2006) Epidermis-restricted expression of zebrafish cytokeratin II is controlled by a -141/+85 minimal promoter, and cassette -141/-111 is essential for driving the tissue specificity. Differentiation.. 74(4):186-194
Wang, Y.H., Chen, Y.H., Wu, T.N., Lin, Y.J., and Tsai, H.J. (2006) A keratin 18 transgenic zebrafish Tg(k18(2.9):RFP) treated with inorganic arsenite reveals visible overproliferation of epithelial cells. Toxicol. Lett.. 163(3):191-197
Wang, Y.H., Chen, Y.H., Lu, J.H., and Tsai, H.J. (2005) A 23-amino Acid motif spanning the basic domain targets zebrafish myogenic regulatory factor myf5 into nucleolus. DNA Cell Biol.. 24(10):651-660
Lin, C.Y., Chen, Y.H., Lee, H.C., and Tsai, H.J. (2004) Novel cis-element in intron 1 represses somite expression of zebrafish myf-5. Gene. 334:63-72
Chen, Y.-H., Lee, H.-C., Liu, C.-F., Lin, C.-Y., and Tsai, H.-J. (2003) Novel regulatory sequence -82/-62 functions as a key element to drive the somite-specificity of zebrafish myf-5. Dev. Dyn.. 228(1):41-50
Chen, Y.-H. and Tsai, H.-J. (2002) Treatment with Myf5-morpholino results in somite patterning and brain formation defects in zebrafish. Differentiation.. 70(8):447-456
Chen, Y.-H., Liang, C.-T., and Tsai, H.-J. (2002) Expression, purification and DNA-binding activity of tilapia muscle-specific transcription factor, MyoD, produced in Escherichia coli. Comp. Biochem. Physiol. B Biochem. Mol. Biol.. 131(4):795-805
Wang, T.-M., Chen, Y.-H., Liu, C.-F., and Tsai, H.-J. (2002) Functional analysis of the proximal promoter regions of fish rhodopsin and myf-5 genes using transgenesis. Mar. Biotechnol.. 4(3):247-255
Chen, Y.-H., Lee, W.-C., Liu, C.-F., and Tsai, H.-J. (2001) Molecular structure, dynamic expression, and promoter analysis of zebrafish (Danio rerio) myf-5 gene. Genesis. 29(1):22-35
Chen, Y.-H., Lee, W.-C., Cheng, C.-H., and Tsai, H.-J. (2000) Muscle regulatory factor gene: zebrafish (Danio rerio) myogenin cDNA. Comp. Biochem. Physiol. B Biochem. Mol. Biol.. 127(1):97-103

Non-Zebrafish Publications: