Research
General Information
ZIRC
ZFIN: Gene: ldha
ZFIN ID: ZDB-GENE-991026-5

Gene Name:lactate dehydrogenase A4
Gene Symbol: ldha
Previous Names: ldha1(1)


GENE EXPRESSION:(current status)
All expression data: 7 figure(s) from 3 publications
Directly submitted expression data: 4 figure(s) (6 images) from Thisse et al., 2004 [MGC:55215]
Wild Type Stages, Structures: Segmentation:20-25 somites (19.00h-22.00h) to Adult (90d-730d, breeding adult)
  cranial ganglion, diencephalon ... (all 15)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Phenotype: (current status)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process response to hypoxia (more)
Cellular Component cytoplasm
Molecular Function L-lactate dehydrogenase activity (more)
All GO Terms (12)

Protein Families, Domains and Sites:
  • InterPro:IPR001236 (1)
  • InterPro:IPR001557 (1)
  • InterPro:IPR011304 (1)
  • InterPro:IPR015955 (1)
  • InterPro:IPR016040 (1)
  • InterPro:IPR018177 (1)
  • InterPro:IPR022383 (1)
  • PROSITE:PS00064 (1)
  • Pfam:PF00056 (1)
  • Pfam:PF02866 (1)
  • EC:1.1.1.27 (1)
  • Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    ldha Contains [SNP] rs3729373 (1) , rs3729374 (1) , rs3729375 (1)
    ldha Contains [STS] chunp30590
    ldha Encodes [cDNA] MGC:55215 (1)    (order this) , MGC:76821 (1)    (order this) , MGC:192397 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131246 (1) 2157 bp
    Polypeptide UniProtKB:Q7ZVJ4 (1) 333 aa
    Sequence Clusters UniGene:4212 (1)
    All Sequence Information (13)

    OTHER  ldha  GENE / MARKER PAGES:

  • Entrez Gene:30496 (1)
  • Ensembl(Zv8):ENSDARG00000040856 (1)

  • MAPPING INFORMATION:
      LG:  25  Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish ldha  25
    Human LDHA  11 (p15.4)
  • OMIM:150000
  • Entrez Gene:3939
  • Orthology Details

    CITATIONS   (19)