ZFIN: Gene: eya1

ZFIN ID: ZDB-GENE-990712-18

Gene Name:eyes absent homolog 1

Gene Symbol: eya1

Previous Names: wu:fc13c10, dog eared(1) , zgc:100770, dog(1)
Nomenclature History

GENE EXPRESSION:(current status)

All expression data:	42 figure(s) from 24 publications
Directly submitted expression data:	10 figure(s) (24 images) from Rauch et al., 2003 [fc13c10]
Wild Type Stages, Structures:	Cleavage:2-cell (0.75h-1.00h) to Adult (90d-730d, breeding adult)
	adenohypophyseal placode, adenohypophysis ... (all 20)
Curated microarray expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s): 9 genotypes
Allele(s): hi2933Tg, t22744, tc257e, tm90b, to15b ... (all 7)

Phenotype: (current status)

Data:	10 figures from 5 publications
Observed in:	adenohypophysis, adenohypophysis development, adrenocorticotropic hormone secreting cell, anatomical system, anterior crista ... (all 36)

Knockdown reagents: MO1-eya1 (1) , MO2-eya1 (1)

GENE PRODUCTS:

Gene Ontology

Ontology GO Term
Biological Process adenohypophysis development (more)

Molecular Function catalytic activity

All GO Terms (7)

Ontology	GO Term
Biological Process	adenohypophysis development (more)
Molecular Function	catalytic activity

Protein Families, Domains and Sites:

InterPro:IPR005834 (1)
InterPro:IPR006545 (1)

Pfam:PF00702 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

eya1 Contained in	[BAC] DKEY-19O24 (1) (order this)
eya1 Encodes	[EST] fc13c10 (1) (order this) [cDNA] MGC:100770 (1) (order this) , MGC:173810 (1) (order this)

Type	Accession #	Length (bp/aa)
RNA	RefSeq:NM_131193 (1)	4438 bp
Genomic	GenBank:BX510326 (1)	239398 bp
Polypeptide	UniProtKB:Q9W6E8 (1)	609 aa
Sequence Clusters	UniGene:74747 (1)
All Sequence Information (14)

OTHER eya1 GENE / MARKER PAGES:

Entrez Gene:30436 (1)

VEGA:OTTDARG00000021374 (1)

Ensembl(Zv8):ENSDARG00000014259 (1)

MAPPING INFORMATION:

LG: 24 Details

ORTHOLOGY:

CITATIONS (59)