Gene

pparda

ID

ZDB-GENE-990415-212

Name

peroxisome proliferator-activated receptor delta a

Symbol

pparda Nomenclature History

Previous Names

FAAR (1)
PPAR[b]
pparb
NR1C2-A (1)
nr1c2a (1)
NUC1 (1)
PPARbeta-A (1)
wu:fb60c11

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Exhibits sequence-specific DNA binding activity. Involved in neural crest cell development and response to activity. Localizes to chromatin. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including intestine; liver; ovary; pectoral fin; and pharyngeal arch. Orthologous to human PPARD (peroxisome proliferator activated receptor delta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

af342937 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pparda Human Ortholog

No data available

Associated With pparda Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Family	IPR001723	Nuclear hormone receptor
Family	IPR003074	Peroxisome proliferator-activated receptor
Family	IPR003075	Peroxisome proliferator-activated receptor, beta
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily

Domain Details Per Protein

Protein	Length	Nuclear hormone receptor	Nuclear hormone receptor, ligand-binding domain	Nuclear hormone receptor-like domain superfamily	Peroxisome proliferator-activated receptor	Peroxisome proliferator-activated receptor, beta	Zinc finger, NHR/GATA-type	Zinc finger, nuclear hormone receptor-type
UniProtKB:F8W3D2 InterPro	496

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pparda-202 (1) Ensembl	Havana	1735 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations