Gene
egr1
- ID
- ZDB-GENE-980526-320
- Name
- early growth response 1
- Symbol
- egr1 Nomenclature History
- Previous Names
-
- etID309970.14 (1)
- krox-24
- krox24
- wu:fj64b05
- wu:fq25f01
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Involved in embryonic retina morphogenesis in camera-type eye and embryonic viscerocranium morphogenesis. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in asthma and myeloid neoplasm. Is expressed in head; heart; hindbrain neural keel; mesoderm; and nervous system. Orthologous to human EGR1 (early growth response 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 38 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Early growth response, N-terminal | Early growth response protein 1, C-terminal | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|
|
UniProtKB:P26632
|
511 | ||||
|
UniProtKB:B3DKJ7
|
511 |
Interactions and Pathways
No data available
Plasmids
No data available