Gene

sema5bb

ID

ZDB-GENE-130530-778

Name

sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb

Symbol

sema5bb Nomenclature History

Previous Names

zmp:0000000775 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including axonogenesis; negative regulation of axon extension involved in axon guidance; and neural crest cell migration. Predicted to act upstream of or within cell differentiation. Predicted to be active in membrane. Orthologous to human SEMA5B (semaphorin 5B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sema5bb Human Ortholog

No data available

Associated With sema5bb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001627	Sema domain
Domain	IPR016201	PSI domain
Family	IPR027231	Semaphorin
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036352	Sema domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat
Repeat	IPR002165	Plexin repeat

Domain Details Per Protein

Protein	Length	Plexin repeat	PSI domain	Sema domain	Sema domain superfamily	Semaphorin	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M1Q1V7 InterPro	1098

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	sema5bb-201 (1) Ensembl	Ensembl		3,295 nt	Select Tool ZFIN BLAST
mRNA	sema5bb-202 (1) Ensembl	Ensembl		3,653 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations