ZFIN is now using GRCz12tu for Genomic Data
Gene
pecam1a
- ID
- ZDB-GENE-130530-689
- Name
- platelet and endothelial cell adhesion molecule 1a
- Symbol
- pecam1a Nomenclature History
- Previous Names
-
- CD31 (1)
- pecam1
- zmp:0000000686
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be located in anchoring junction; membrane raft; and plasma membrane. Is expressed in midbrain hindbrain boundary and pharyngeal arch. Human ortholog(s) of this gene implicated in acquired thrombocytopenia; artery disease (multiple); neuroblastoma; psoriatic arthritis; and thrombosis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Fowler et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Family | IPR050488 | Immunoglobulin Fc region receptor |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin domain subtype | Immunoglobulin Fc region receptor | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1R1B9 | InterPro | 738 | ||||||
| UniProtKB:A0A8M9PWY1 | InterPro | 723 | ||||||
| UniProtKB:A0JMH1 | InterPro | 746 | ||||||
| UniProtKB:A0A8M1NHB4 | InterPro | 737 | ||||||
| UniProtKB:A0ACD6B6F6 | InterPro | 738 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pecam1a-201
(1)
|
Ensembl | 5,360 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance