Gene

frmd4ba

ID
ZDB-GENE-130412-1
Name
FERM domain containing 4Ba
Symbol
frmd4ba Nomenclature History
Previous Names
  • fb59f02
  • si:dkey-178o16.1
  • wu:fb59f02
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable cytoskeletal protein binding activity. Predicted to act upstream of or within establishment of epithelial cell polarity. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in adherens junction and bicellular tight junction. Orthologous to human FRMD4B (FERM domain containing 4B).
Genome Resources
Note
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa10936Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa16028Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With frmd4ba Human Ortholog
No data available
Associated With frmd4ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019747 FERM conserved site
Domain IPR000299 FERM domain
Domain IPR018979 FERM, N-terminal
Domain IPR018980 FERM, C-terminal PH-like domain
Domain IPR019748 FERM central domain
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Domain Details Per Protein
Protein Length Band 4.1 domain Cytohesin Ubiquitin Protein Inducing Domain Ezrin/radixin/moesin-like FERM/acyl-CoA-binding protein superfamily FERM central domain FERM conserved site FERM, C-terminal PH-like domain FERM domain FERM domain-containing protein 4A/B FERM, N-terminal FERM superfamily, second domain FRMD4A/B, FERM domain C-lobe PH-like domain superfamily Ubiquitin-like domain superfamily
UniProtKB:A0A8M9PN64
InterPro
974
UniProtKB:A0A8M9Q755
InterPro
1016
UniProtKB:A0A8M9PYT3
InterPro
1028
UniProtKB:A0A8M3BAK8
InterPro
1016
UniProtKB:A0A8M9P9D0
InterPro
974
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 6
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA frmd4ba-202 (1)
Ensembl
Ensembl 4,516 nt
ZFIN BLAST
mRNA frmd4ba-205 (1)
Ensembl
Ensembl 912 nt
ZFIN BLAST
mRNA frmd4ba-206 (1)
Ensembl
Ensembl 6,515 nt
ZFIN BLAST
mRNA frmd4ba-207 (1)
Ensembl
Ensembl 6,311 nt
ZFIN BLAST
mRNA frmd4ba-208 (1)
Ensembl
Ensembl 159 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-170N20ZFIN Curated Data
Contained inBACDKEY-178O16ZFIN Curated Data
Contained inBACDKEY-190P17ZFIN Curated Data
EncodesESTfb59f02
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_009302636 (1)4398 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:CU468905 (2)271044 nt
MegaBLAST
PolypeptideUniProtKB:A0A8M9PN59 (1)1028 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanFRMD4B3
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
MouseFrmd4b6
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
TSV
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