Gene
clpxb
- ID
- ZDB-GENE-130404-1
- Name
- caseinolytic mitochondrial matrix peptidase chaperone subunit Xb
- Symbol
- clpxb Nomenclature History
- Previous Names
-
- fc31b05
- fj85g10
- wu:fc31b05
- wu:fj85g10
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to act upstream of or within protein folding. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Orthologous to human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Rondelli et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Protoporphyria, erythropoietic, 2 | 618015 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR010603 | Zinc finger, ClpX C4-type |
| Domain | IPR019489 | Clp ATPase, C-terminal |
| Family | IPR004487 | Clp protease, ATP-binding subunit ClpX |
| Family | IPR050052 | ATP-dependent Clp protease ATP-binding subunit ClpX |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | ATPase, AAA-type, core | ATP-dependent Clp protease ATP-binding subunit ClpX | Clp ATPase, C-terminal | Clp protease, ATP-binding subunit ClpX | P-loop containing nucleoside triphosphate hydrolase | Zinc finger, ClpX C4-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F9J1
|
618 |
Interactions and Pathways
No data available
Plasmids
No data available