Gene
tmem132e
- ID
- ZDB-GENE-120926-3
- Name
- transmembrane protein 132E
- Symbol
- tmem132e Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Acts upstream of or within auditory receptor cell development; detection of mechanical stimulus involved in sensory perception of sound; and posterior lateral line neuromast hair cell development. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 99. Orthologous to human TMEM132E (transmembrane protein 132E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Li et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 99 | Alliance | Deafness, autosomal recessive 99 | 618481 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR031435 | Transmembrane protein TMEM132, N-terminal |
| Domain | IPR031436 | Transmembrane protein TMEM132, C-terminal |
| Domain | IPR031437 | Transmembrane protein family 132, middle domain |
| Domain | IPR055421 | Transmembrane protein TMEM132, cohesin-like domain |
| Domain | IPR055422 | Transmembrane protein TMEM132, second Ig-like domain |
| Domain | IPR055423 | Transmembrane protein TMEM132, fifth domain |
| Domain | IPR055424 | Transmembrane protein TMEM132, sixth domain |
| Family | IPR026307 | Transmembrane protein 132 |
Domain Details Per Protein
| Protein | Additional Resources | Length | Transmembrane protein 132 | Transmembrane protein family 132, middle domain | Transmembrane protein TMEM132, cohesin-like domain | Transmembrane protein TMEM132, C-terminal | Transmembrane protein TMEM132, fifth domain | Transmembrane protein TMEM132, N-terminal | Transmembrane protein TMEM132, second Ig-like domain | Transmembrane protein TMEM132, sixth domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3ASS8 | InterPro | 1070 | ||||||||
| UniProtKB:L7VG99 | InterPro | 1073 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem132e-201
(1)
|
Ensembl | 3,795 nt | ||
| mRNA |
tmem132e-202
(1)
|
Ensembl | 4,872 nt | ||
| mRNA |
tmem132e-203
(1)
|
Ensembl | 3,657 nt |
Interactions and Pathways
No data available
Plasmids
No data available