Gene
dchs1a
- ID
- ZDB-GENE-120410-3
- Name
- dachsous cadherin-related 1a
- Symbol
- dchs1a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Orthologous to human DCHS1 (dachsous cadherin-related 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Li-Villarreal et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitral valve prolapse | Alliance | Mitral valve prolapse 2 | 607829 |
| Van Maldergem syndrome 1 | Alliance | Van Maldergem syndrome 1 | 601390 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily |
|---|---|---|---|---|---|
|
UniProtKB:X1WDW2
|
3275 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dchs1a-201
(1)
|
Ensembl | 12,286 nt | ||
| mRNA |
dchs1a-202
(1)
|
Ensembl | 9,970 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance