Gene
tspeara
- ID
- ZDB-GENE-120215-12
- Name
- thrombospondin-type laminin G domain and EAR repeats a
- Symbol
- tspeara Nomenclature History
- Previous Names
-
- si:ch73-267f5.4
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Acts upstream of or within bone morphogenesis and regulation of odontogenesis. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 98; ectodermal dysplasia 14; and tooth agenesis. Orthologous to human TSPEAR (thrombospondin type laminin G domain and EAR repeats).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 98 | Alliance | ?Deafness, autosomal recessive 98 | 614861 |
| ectodermal dysplasia 14 | Alliance | Ectodermal dysplasia 14, hypohidrotic/hair/tooth/nail type | 618180 |
| Tooth agenesis, selective, 10 | 620173 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Concanavalin A-like lectin/glucanase domain superfamily | EAR | Laminin G domain | Leucine-rich glioma-inactivated , EPTP repeat | Thrombospondin-like, N-terminal domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:E7EY40 | InterPro | 676 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tspeara-201
(1)
|
Ensembl | 2,031 nt | ||
| mRNA |
tspeara-202
(1)
|
Ensembl | 2,010 nt | ||
| mRNA |
tspeara-203
(1)
|
Ensembl | 2,013 nt | ||
| mRNA |
tspeara-204
(1)
|
Ensembl | 1,596 nt |
Interactions and Pathways
No data available
Plasmids
No data available