Gene

ago1

ID

ZDB-GENE-110606-3

Name

argonaute RISC component 1

Symbol

ago1 Nomenclature History

Previous Names

Ago1 (1)
eif2c1
si:ch211-119n15.3

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have nucleic acid binding activity. Predicted to be involved in gene silencing by RNA. Is expressed in several structures, including eye; fin; integument; pleuroperitoneal region; and post-vent region. Orthologous to human AGO1 (argonaute RISC component 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ago1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	620292

Associated With ago1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003100	PAZ domain
Domain	IPR003165	Piwi domain
Domain	IPR014811	Argonaute, linker 1 domain
Domain	IPR032472	Argonaute linker 2 domain
Domain	IPR032473	Protein argonaute, Mid domain
Domain	IPR032474	Protein argonaute, N-terminal
Domain	IPR045246	Argonaute-like, PIWI domain
Homologous_superfamily	IPR012337	Ribonuclease H-like superfamily
Homologous_superfamily	IPR036085	PAZ domain superfamily
Homologous_superfamily	IPR036397	Ribonuclease H superfamily