Gene
cd44b
- ID
- ZDB-GENE-110429-2
- Name
- CD44 molecule (IN blood group) b
- Symbol
- cd44b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable hyaluronic acid binding activity and transmembrane signaling receptor activity. Predicted to contribute to cytokine receptor activity. Predicted to be involved in cell adhesion; inflammatory response; and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in membrane and microvillus. Predicted to be part of macrophage migration inhibitory factor receptor complex. Predicted to be active in basolateral plasma membrane. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (Indian blood group)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Blood group, Indian system] | 609027 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CD44 antigen | CD44 antigen-like | C-type lectin fold | C-type lectin-like/link domain superfamily | Link domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z4J5
|
401 | |||||
|
UniProtKB:A0A8M6Z569
|
412 | |||||
|
UniProtKB:A0A8M3APC4
|
414 | |||||
|
UniProtKB:A0A8M6YYL8
|
421 |
Interactions and Pathways
No data available
Plasmids