Gene
mid1
- ID
- ZDB-GENE-110411-205
- Name
- midline 1
- Symbol
- mid1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have zinc ion binding activity. Human ortholog(s) of this gene implicated in Opitz-GBBB syndrome. Orthologous to human MID1 (midline 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Opitz GBBB syndrome | Alliance | Opitz GBBB syndrome | 300000 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003649 | B-box, C-terminal |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR003879 | Butyrophylin-like, SPRY domain |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR017903 | COS domain |
| Domain | IPR027370 | Zinc finger, RING-type, eukaryotic |
| Domain | IPR040859 | Midline-1, COS domain |
| Domain | IPR047095 | Midline-1, B-box-type 1 zinc finger |
| Family | IPR050617 | E3 ubiquitin-protein ligases and FN3/SPRY domain-containing proteins |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | B-box, C-terminal | B-box-type zinc finger | Butyrophylin-like, SPRY domain | Concanavalin A-like lectin/glucanase domain superfamily | COS domain | E3 ubiquitin-protein ligases and FN3/SPRY domain-containing proteins | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Midline-1, B-box-type 1 zinc finger | Midline-1, COS domain | SPRY domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, RING-type, eukaryotic |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AWB4
|
667 | ||||||||||||||||||
|
UniProtKB:A0A8M3B2Y2
|
453 |
Interactions and Pathways
No data available
Plasmids
No data available