Gene
slc25a38b
- ID
- ZDB-GENE-110214-1
- Name
- solute carrier family 25 member 38b
- Symbol
- slc25a38b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable glycine transmembrane transporter activity. Involved in erythrocyte differentiation. Acts upstream of or within hemoglobin biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in blood; blood island; and posterior cardinal vein. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 2. Orthologous to human SLC25A38 (solute carrier family 25 member 38).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Fernández-Murray et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive pyridoxine-refractory sideroblastic anemia 2 | Alliance | Anemia, sideroblastic, 2, pyridoxine-refractory | 205950 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Mitochondrial carrier domain superfamily | Mitochondrial carrier protein | Mitochondrial glycine transporter Hem25/SLC25A38 | Mitochondrial substrate/solute carrier |
|---|---|---|---|---|---|
|
UniProtKB:P0CAT2
|
287 | ||||
|
UniProtKB:A0A8M9Q680
|
299 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc25a38b-201
(1)
|
Ensembl | 789 nt | ||
| mRNA |
slc25a38b-202
(1)
|
Ensembl | 3,947 nt |
Interactions and Pathways
No data available
Plasmids
No data available