Gene

zbtb16b

ID
ZDB-GENE-100923-1
Name
zinc finger and BTB domain containing 16b
Symbol
zbtb16b Nomenclature History
Previous Names
  • plzfb (1)
  • wu:fb53a11
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in positive regulation of type I interferon production. Localizes to nucleus. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; integument; liver; and pleuroperitoneal region. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With zbtb16b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leukemia, acute promyelocytic, PL2F/RARA type
Associated With zbtb16b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain SKP1/BTB/POZ domain superfamily Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:E7FGS1 659
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations