Gene

adap2

ID
ZDB-GENE-070912-21
Name
ArfGAP with dual PH domains 2
Symbol
adap2 Nomenclature History
Previous Names
  • si:ch211-11k18.11 (1)
  • si:ch73-33i10.5
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity; metal ion binding activity; and phosphatidylinositol bisphosphate binding activity. Involved in atrioventricular valve development; heart jogging; and heart looping. Predicted to localize to intracellular membrane-bounded organelle and plasma membrane. Is expressed in several structures, including digestive system; gonad; head; heart; and skeletal muscle. Orthologous to human ADAP2 (ArfGAP with dual PH domains 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Venturin et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adap2 Human Ortholog
No data available
Associated With adap2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001164 Arf GTPase activating protein
Domain IPR001849 Pleckstrin homology domain
Domain IPR037849 ADAP, PH domain 1
Domain IPR037851 ADAP, PH domain 2
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR037278 ARFGAP/RecO-like zinc finger
Homologous_superfamily IPR038508 ArfGAP domain superfamily
Domain Details Per Protein
Protein Length ADAP, PH domain 1 ADAP, PH domain 2 ArfGAP domain superfamily ARFGAP/RecO-like zinc finger Arf GTPase activating protein PH-like domain superfamily Pleckstrin homology domain
UniProtKB:A0A8M9Q881 418
UniProtKB:E9QE78 378
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations