Gene
mrap2b
- ID
- ZDB-GENE-100729-5
- Name
- melanocortin 2 receptor accessory protein 2b
- Symbol
- mrap2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Exhibits receptor regulator activity and type 4 melanocortin receptor binding activity. Involved in several processes, including energy homeostasis; energy reserve metabolic process; and positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway. Localizes to Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in obesity. Is expressed in several structures, including adipose tissue; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to human MRAP2 (melanocortin 2 receptor accessory protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {?Obesity, susceptibility to, BMIQ18} | 615457 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR028111 | Melanocortin-2 receptor accessory protein family |
Domain Details Per Protein
| Protein | Length | Melanocortin-2 receptor accessory protein family |
|---|---|---|
|
UniProtKB:P0DM64
|
199 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available