Gene

nrtn

ID
ZDB-GENE-100427-6
Name
neurturin
Symbol
nrtn Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable growth factor activity. Predicted to be involved in system development. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Orthologous to human NRTN (neurturin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
No data available
Human Disease
Associated With nrtn Human Ortholog
No data available
Associated With nrtn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001839 Transforming growth factor-beta, C-terminal
Family IPR043401 Glial cell line-derived neurotrophic factor family
Homologous_superfamily IPR029034 Cystine-knot cytokine
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length Cystine-knot cytokine Glial cell line-derived neurotrophic factor family Transforming growth factor-beta, C-terminal
UniProtKB:E7FAV4 InterPro 211
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nrtn-201 (1) Ensembl 993 nt
mRNA nrtn-202 (1) Ensembl 2,348 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-224J12
1 - 1 of 1
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNRTN19
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
MouseNrtn17
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
Citations