Gene

nhlrc2

ID

ZDB-GENE-100318-2

Name

NHL repeat containing 2

Symbol

nhlrc2 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to be involved in cell redox homeostasis. Orthologous to human NHLRC2 (NHL repeat containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Uusimaa et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nhlrc2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		FINCA syndrome	618278

Associated With nhlrc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR012336	Thioredoxin-like fold
Domain	IPR013766	Thioredoxin domain
Domain	IPR045302	NHL2, NHL repeat domain
Homologous_superfamily	IPR011042	Six-bladed beta-propeller, TolB-like
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily
Repeat	IPR001258	NHL repeat

Domain Details Per Protein

Protein	Length	NHL2, NHL repeat domain	NHL repeat	Six-bladed beta-propeller, TolB-like	Thioredoxin domain	Thioredoxin-like fold	Thioredoxin-like superfamily
UniProtKB:A0A8M3BE96 InterPro	719

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nhlrc2-201 (1) Ensembl	Havana	5008 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations