ZFIN is now using GRCz12tu for Genomic Data
Gene
nlgn4xa
- ID
- ZDB-GENE-100309-2
- Name
- neuroligin 4 X-linked a
- Symbol
- nlgn4xa Nomenclature History
- Previous Names
-
- nlgn4a
- nlgn4b (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable neurexin family protein binding activity. Predicted to be involved in synapse assembly. Predicted to be located in dendrite; plasma membrane; and synapse. Predicted to be active in postsynaptic specialization membrane. Is expressed in several structures, including brain; eye; gonad; spinal cord interneuron; and swim bladder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to several human genes including NLGN4X (neuroligin 4 X-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|---|---|
| UniProtKB:R4GE10 | InterPro | 826 | |||||
| UniProtKB:A0A8M9QBU0 | InterPro | 844 | |||||
| UniProtKB:D0EVX4 | InterPro | 826 | |||||
| UniProtKB:A0AB32TRR4 | InterPro | 843 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nlgn4xa-201
(1)
|
Ensembl | 5,478 nt | ||
| mRNA |
nlgn4xa-202
(1)
|
Ensembl | 2,532 nt | ||
| mRNA |
nlgn4xa-203
(1)
|
Ensembl | 4,719 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers