Gene

ksr1a

ID

ZDB-GENE-091113-34

Name

kinase suppressor of ras 1a

Symbol

ksr1a Nomenclature History

Previous Names

si:dkey-174l22.2

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in Ras protein signal transduction. Orthologous to human KSR1 (kinase suppressor of ras 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ksr1a Human Ortholog

No data available

Associated With ksr1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000719	Protein kinase domain
Domain	IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR046861	Kinase suppressor RAS 1, N-terminal helical hairpin
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily
Homologous_superfamily	IPR046933	Kinase suppressor RAS 1, N-terminal helical hairpin superfamily

Domain Details Per Protein

Protein	Length	C1-like domain superfamily	Kinase suppressor RAS 1, N-terminal helical hairpin	Kinase suppressor RAS 1, N-terminal helical hairpin superfamily	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Protein kinase domain	Protein kinase-like domain superfamily	Serine-threonine/tyrosine-protein kinase, catalytic domain	Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A8M3B3K1 InterPro	898
UniProtKB:A0A8M1QUL5 InterPro	970

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ksr1a-201 (1) Ensembl	Havana	539 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ksr1a-202 (1) Ensembl	Havana	3078 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations