Gene

tmod1

ID

ZDB-GENE-090312-131

Name

tropomodulin 1

Symbol

tmod1 Nomenclature History

Previous Names

si:ch211-288h2.6

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Predicted to localize to striated muscle thin filament. Is expressed in muscle. Orthologous to human TMOD1 (tropomodulin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Davidson et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tmod1 Human Ortholog

No data available

Associated With tmod1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR004934	Tropomodulin
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily

Domain Details Per Protein

Protein	Length	Leucine-rich repeat domain superfamily	Tropomodulin
UniProtKB:E9QGR6 InterPro	356
UniProtKB:A0A8M9QDI7 InterPro	243
UniProtKB:A0A8M9PX33 InterPro	378

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	tmod1-201 (1) Ensembl	Ensembl		1,266 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-tmod1	polyclonal	tmod1	IgG	Rabbit	IHC	Proteintech	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations