Gene

cep170aa

ID

ZDB-GENE-090312-109

Name

centrosomal protein 170Aa

Symbol

cep170aa Nomenclature History

Previous Names

cep170 (1)
cep170a
si:ch211-227c6.4

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to be involved in several processes, including microtubule organizing center organization; neuron migration; and tube formation. Predicted to act upstream of or within cell projection organization and centrosome cycle. Predicted to be located in several cellular components, including cell junction; cell projection; and cytoskeleton. Predicted to be active in centriole and centrosome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 16 and Senior-Loken syndrome. Orthologous to several human genes including SDCCAG8 (SHH signaling and ciliogenesis regulator SDCCAG8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cep170aa Human Ortholog

No data available

Associated With cep170aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000253	Forkhead-associated (FHA) domain
Domain	IPR029300	CEP170, C-terminal
Family	IPR051176	Centrosomal and Immune Signaling Modulators
Homologous_superfamily	IPR008984	SMAD/FHA domain superfamily

Domain Details Per Protein

Protein	Length	Centrosomal and Immune Signaling Modulators	CEP170, C-terminal	Forkhead-associated (FHA) domain	SMAD/FHA domain superfamily
UniProtKB:A0A8M9PBF0 InterPro	1479
UniProtKB:A0A8M9PYF0 InterPro	1352
UniProtKB:A0A8M3B539 InterPro	1482
UniProtKB:A0A8M9QNN4 InterPro	1502
UniProtKB:A0A8M9Q177 InterPro	1482
UniProtKB:A0A8M3BEI8 InterPro	1502
UniProtKB:F1QAR8 InterPro	1479
UniProtKB:A0A8M9QK29 InterPro	1489
UniProtKB:A0A8M3AYY4 InterPro	1505
UniProtKB:A0A8M3B7W1 InterPro	1489
UniProtKB:A0A8M9PMX2 InterPro	1352
UniProtKB:A0A8M3AYY9 InterPro	1141
UniProtKB:A0A8M9Q4Z9 InterPro	1498
UniProtKB:A0A8M9PU32 InterPro	1505
UniProtKB:A0A8M3AYX2 InterPro	1498

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cep170aa-201 (1) Ensembl	Ensembl	7,401 nt	Select Tool ZFIN BLAST
mRNA	cep170aa-202 (1) Ensembl	Ensembl	6,847 nt	Select Tool ZFIN BLAST
mRNA	cep170aa-204 (1) Ensembl	Ensembl	285 nt	Select Tool ZFIN BLAST
ncRNA	cep170aa-003 (1) Ensembl	Ensembl	429 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations