Gene

soat1

ID
ZDB-GENE-081105-177
Name
sterol O-acyltransferase 1
Symbol
soat1 Nomenclature History
Previous Names
  • si:dkey-21p1.4
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have cholesterol O-acyltransferase activity; cholesterol binding activity; and fatty-acyl-CoA binding activity. Predicted to be involved in cholesterol efflux; cholesterol esterification; and cholesterol metabolic process. Predicted to localize to endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Is expressed in several structures, including eye; hatching gland; pericardial region; pleuroperitoneal region; and yolk syncytial layer. Orthologous to several human genes including SOAT1 (sterol O-acyltransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Chang et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With soat1 Human Ortholog
No data available
Associated With soat1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004299 Membrane bound O-acyl transferase, MBOAT
Family IPR014371 Sterol O-acyltransferase, ACAT/DAG/ARE types
Domain Details Per Protein
Protein Length Membrane bound O-acyl transferase, MBOAT Sterol O-acyltransferase, ACAT/DAG/ARE types
UniProtKB:B0UYE4 554
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations