Gene
cdk12
- ID
- ZDB-GENE-081104-294
- Name
- cyclin dependent kinase 12
- Symbol
- cdk12 Nomenclature History
- Previous Names
-
- si:ch73-79d13.1
- wu:fa01h10
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity; cyclin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in phosphorylation of RNA polymerase II C-terminal domain and positive regulation of transcription elongation by RNA polymerase II. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Orthologous to human CDK12 (cyclin dependent kinase 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclin-dependent kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
|
UniProtKB:F1R6Y1
|
1293 |
Interactions and Pathways
No data available
Plasmids
No data available