Gene

fhod3b

ID

ZDB-GENE-081028-61

Name

formin homology 2 domain containing 3b

Symbol

fhod3b Nomenclature History

Previous Names

si:ch211-209d1.1
zgc:103746

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to be involved in actin filament organization. Orthologous to human FHOD3 (formin homology 2 domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fhod3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cardiomyopathy, familial hypertrophic, 28	619402

Associated With fhod3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR014767	Diaphanous autoregulatory (DAD) domain
Domain	IPR014768	Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Domain	IPR015425	Formin, FH2 domain
Domain	IPR041387	FHOD1, N-terminal GTPase-binding domain
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR042201	Formin, FH2 domain superfamily

Domain Details Per Protein

Protein	Length	Armadillo-like helical	Armadillo-type fold	Diaphanous autoregulatory (DAD) domain	FHOD1, N-terminal GTPase-binding domain	Formin, FH2 domain	Formin, FH2 domain superfamily	Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
UniProtKB:A0A8M9PDK4 InterPro	1516
UniProtKB:A0A8M9PK03 InterPro	1692
UniProtKB:A0A8M9PC43 InterPro	147
UniProtKB:A0A8M9P8A0 InterPro	1532
UniProtKB:A0A8M9PNP0 InterPro	133
UniProtKB:A0A8M9NZN4 InterPro	1557

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fhod3b-201 (1) Ensembl	Havana	2542 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fhod3b-203 (1) Ensembl	Havana	959 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	fhod3b-003 (1) Ensembl	Havana	917 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations