Gene

ppef1

ID

ZDB-GENE-080303-27

Name

protein phosphatase, EF-hand calcium binding domain 1

Symbol

ppef1 Nomenclature History

Previous Names

zgc:171580 (1)

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in detection of stimulus involved in sensory perception. Predicted to be active in cytosol and nucleus. Orthologous to human PPEF1 (protein phosphatase with EF-hand domain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppef1 Human Ortholog

No data available

Associated With ppef1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Domain	IPR004843	Calcineurin-like phosphoesterase domain, ApaH type
Domain	IPR006186	Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Domain	IPR013235	PPP domain
Family	IPR012008	Serine/threonine-protein phosphatase with EF-hands
Family	IPR051134	Protein Phosphatase PPP
Homologous_superfamily	IPR029052	Metallo-dependent phosphatase-like

Domain Details Per Protein

Protein	Length	Calcineurin-like phosphoesterase domain, ApaH type	EF-Hand 1, calcium-binding site	EF-hand domain	Metallo-dependent phosphatase-like	PPP domain	Protein Phosphatase PPP	Serine/threonine-protein phosphatase with EF-hands	Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
UniProtKB:B0JZB7 InterPro	718
UniProtKB:A0A8M9PUY6 InterPro	718
UniProtKB:A0A8M9QHP8 InterPro	729

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ppef1-201 (1) Ensembl	Ensembl	3,256 nt	Select Tool ZFIN BLAST
mRNA	ppef1-202 (1) Ensembl	Ensembl	3,192 nt	Select Tool ZFIN BLAST
mRNA	ppef1-203 (1) Ensembl	Ensembl	2,338 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations