Gene

arid1aa

ID

ZDB-GENE-080220-35

Name

AT-rich interaction domain 1Aa

Symbol

arid1aa Nomenclature History

Previous Names

fb79b07
fb95g08
wu:fb79b07
wu:fb95g08
zgc:171438

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to contribute to nucleosome binding activity. Predicted to be involved in ATP-dependent chromatin remodeling; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Predicted to localize to SWI/SNF complex; nBAF complex; and nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 2 and neuroblastoma. Is expressed in hindbrain and neurons. Orthologous to human ARID1A (AT-rich interaction domain 1A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7144643 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arid1aa Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Coffin-Siris syndrome 2	Alliance	Coffin-Siris syndrome 2	614607

Associated With arid1aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001606	ARID DNA-binding domain
Domain	IPR030094	AT-rich interactive domain-containing protein 1A, ARID/BRIGHT DNA binding domain
Domain	IPR033388	SWI/SNF-like complex subunit BAF250, C-terminal
Family	IPR021906	SWI/SNF-like complex subunit BAF250/Osa
Homologous_superfamily	IPR036431	ARID DNA-binding domain superfamily