Gene
hbegfa
- ID
- ZDB-GENE-080204-119
- Name
- heparin-binding EGF-like growth factor a
- Symbol
- hbegfa Nomenclature History
- Previous Names
-
- zgc:175091
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Involved in retina development in camera-type eye and sensory epithelium regeneration. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in perinatal necrotizing enterocolitis. Is expressed in retina. Orthologous to human HBEGF (heparin binding EGF like growth factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from El-Brolosy et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Diphtheria, susceptibility to} |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
Domain Details Per Protein
| Protein | Length | EGF-like domain |
|---|---|---|
|
UniProtKB:A9JRW9
|
230 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hbegfa-201
(1)
|
Ensembl | 1,808 nt | ||
| ncRNA |
hbegfa-002
(1)
|
Ensembl | 760 nt |
Interactions and Pathways
No data available
Plasmids
No data available