Gene

prkd1

ID
ZDB-GENE-080131-1
Name
protein kinase D1
Symbol
prkd1 Nomenclature History
Previous Names
  • PKD1 (1)
  • si:dkeyp-47g2.1
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; calcium-dependent protein kinase C activity; and metal ion binding activity. Involved in regulation of angiogenesis and regulation of lymphangiogenesis. Predicted to localize to cytoplasm. Orthologous to human PRKD1 (protein kinase D1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Hollenbach et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Hollenbach et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa6481Allele with one point mutationUnknownSplice SiteENU
sa23102Allele with one point mutationUnknownSplice SiteENU
1 - 2 of 2
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Sequence Targeting Reagents
Human Disease
Associated With prkd1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Congenital heart defects and ectodermal dysplasia 617364
1 - 1 of 1
Associated With prkd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
1 - 5 of 10 Show all
Domain Details Per Protein
Protein Length C1-like domain superfamily Diacylglycerol/phorbol-ester binding PH-like domain superfamily Pleckstrin homology domain Protein kinase, ATP binding site Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase C mu-related Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A8M9PPI9 878
UniProtKB:X1WHC7 886
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 17
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prkd1-201 (1) Ensembl 2,637 nt
mRNA prkd1-202 (1) Ensembl 3,886 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-prkd1 polyclonal Rabbit
Santa Cruz Biotechnology, Inc.
2
1 - 1 of 1
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEYP-47G2ZFIN Curated Data
1 - 1 of 1
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanPRKD114
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MousePrkd112
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations