ZFIN is now using GRCz12tu for Genomic Data
Gene
brinp2
- ID
- ZDB-GENE-070912-621
- Name
- bone morphogenetic protein/retinoic acid inducible neural-specific 2
- Symbol
- brinp2 Nomenclature History
- Previous Names
-
- fam5b
- si:dkey-9e8.1
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in cellular response to retinoic acid; central nervous system neuron differentiation; and negative regulation of mitotic cell cycle. Predicted to act upstream of or within positive regulation of neuron differentiation and regulation of cell cycle. Predicted to be active in cytoplasm; dendrite; and neuronal cell body. Is expressed in several structures, including fin bud; gill; head; heart; and muscle. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human BRINP2 (BMP/retinoic acid inducible neural specific 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Giousoh et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Thyme et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | BMP/retinoic acid-inducible neural-specific protein | Membrane attack complex component/perforin (MACPF) domain |
|---|---|---|---|---|
| UniProtKB:A0A0G2UMG0 | InterPro | 774 | ||
| UniProtKB:A0A8M1P6S6 | InterPro | 776 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
brinp2-201
(1)
|
Ensembl | 3,117 nt | ||
| mRNA |
brinp2-202
(1)
|
Ensembl | 2,325 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers