Gene
zeb2a
- ID
- ZDB-GENE-070912-553
- Name
- zinc finger E-box binding homeobox 2a
- Symbol
- zeb2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in several processes, including chordate embryonic development; convergent extension; and negative regulation of fibroblast growth factor receptor signaling pathway. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Is expressed in several structures, including head; nervous system; neural plate; neuroectoderm; and tail bud. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu412 (26 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mowat-Wilson syndrome | Alliance | Mowat-Wilson syndrome | 235730 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Drought induced 19 protein type, zinc-binding domain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:B5DE38
|
1175 | |||
|
UniProtKB:F1QY45
|
1218 | |||
|
UniProtKB:A0A8M9Q4G0
|
1095 | |||
|
UniProtKB:B0LVE9
|
1201 | |||
|
UniProtKB:A0A8M2BFJ5
|
1192 |
Interactions and Pathways
No data available
Plasmids
No data available